SIGLEC7 Protein (AA 19-353) (His tag)

Catalog No. ABIN7013595

Product Details

Target: SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))

Protein Type: Recombinant

Biological Activity: Active

Protein Characteristics: AA 19-353

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This SIGLEC7 protein is labelled with His tag.

Sequence: AA 19-353

Characteristics: Biotinylated Human SIRP alphaV2 / CD172a Protein, His,Avitag™

Purity: >95 % as determined by SDS-PAGE.

Endotoxin Level: Less than 1.0 EU per μg by the LAL method.

Application Details

Application Notes: MALS verified

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 25 mM MES, 150 mM NaCl, pH 5.5

Storage: -20 °C

Target Details

Target: SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))

Alternative Name: Siglec-7 (SIGLEC7 Products)

Synonyms: SIGLEC7 Protein, AIRM1 Protein, CD328 Protein, CDw328 Protein, D-siglec Protein, QA79 Protein, SIGLEC-7 Protein, SIGLEC19P Protein, SIGLECP2 Protein, p75 Protein, p75/AIRM1 Protein, sialic acid-binding Ig-like lectin 7 Protein, sialic acid binding Ig like lectin 7 Protein, LOC468976 Protein, SIGLEC7 Protein

Background: Siglec-7 is a member of the human CD33-related Siglec receptor. The extracellular region of Siglec-7 is characterized by an N-terminal V-set Ig domain that can bind sialic acid and two C2-set Ig domains. The cytoplasmic tail of Siglec-7 has one immune-receptor tyrosine-based inhibitory motif (ITIM) and one ITIM-like motif. Siglec-7 is considered as a sialic acid-dependent immunoreceptor with inhibitory potential and expressed predominantly on human NK cells, monocytes and a small subset of CD8+ T cells.

Molecular Weight: 38.8 kDa

NCBI Accession: NP_055200