SIGLEC7 Protein (AA 19-353) (hIgG-His-tag)
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- Target See all SIGLEC7 Proteins
- SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 19-353
- Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This SIGLEC7 protein is labelled with hIgG-His-tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- ADPQKSNRKD YSLTMQSSVT VQEGMCVHVR CSFSYPVDSQ TDSDPVHGYW FRAGNDISWK APVATNNPAW AVQEETRDRF HLLGDPQTKN CTLSIRDARM SDAGRYFFRM EKGNIKWNYK YDQLSVNVTA LTHRPNILIP GTLESGCFQN LTCSVPWACE QGTPPMISWM GTSVSPLHPS TTRSSVLTLI PQPQHHGTSL TCQVTLPGAG VTTNRTIQLN VSYPPQNLTV TVFQGEGTAS TALGNSSSLS VLEGQSLRLV CAVDSNPPAR LSWTWRSLTL YPSQPSNPLV LELQVHLGDE GEFTCRAQNS LGSQHVSLNL SLQQEYTGKM RPVSGVLLLE PKSCDKTHTC PPCPAPELLG GPSVFLFPPK PKDTLMISRT PEVTCVVVDV SHEDPEVKFN WYVDGVEVHN AKTKPREEQY NSTYRVVSVL TVLHQDWLNG KEYKCKVSNK ALPAPIEKTI SKAKGQPREP QVYTLPPSRD ELTKNQVSLT CLVKGFYPSD IAVEWESNGQ PENNYKTTPP VLDSDGSFFL YSKLTVDKSR WQQGNVFSCS VMHEALHNHY TQKSLSLSPG KHHHHHH
- Purity
- > 90 % by SDS - PAGE
- Endotoxin Level
- < 1.0 EU per 1ug of protein (determined by LAL method)
- Top Product
- Discover our top product SIGLEC7 Protein
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Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7) (AA 377-466) protein (GST tag)
SIGLEC7 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7) (AA 1-467) protein (GST tag)SIGLEC7 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7) (AA 19-353) protein (His tag)Crystallography grade SIGLEC7 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7) (AA 19-467) protein (rho-1D4 tag)Crystallography grade SIGLEC7 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7) (AA 19-353) (Active) protein (His tag)SIGLEC7 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))
- Alternative Name
- SIGLEC7 (SIGLEC7 Products)
- Synonyms
- SIGLEC7 Protein, AIRM1 Protein, CD328 Protein, CDw328 Protein, D-siglec Protein, QA79 Protein, SIGLEC-7 Protein, SIGLEC19P Protein, SIGLECP2 Protein, p75 Protein, p75/AIRM1 Protein, sialic acid-binding Ig-like lectin 7 Protein, sialic acid binding Ig like lectin 7 Protein, LOC468976 Protein, SIGLEC7 Protein
- Background
- SIGLEC7, also known as sialic acid-binding Ig-like lectin 7 isoform 1, is a recently discovered family of sialic acid-binding lectins of the immunoglobulin (Ig) superfamily. The extracellular portion has two Ig-like domains, with the amino-terminal V-set Ig domain including amino acid residues known to be involved in sialic acid recognition by other Siglecs. The combination of an extracellular sialic acid binding site and an intracellular ITIM motif suggests that this molecule is involved in trans-membrane regulatory signaling reactions. It exists as a monomer on the cell surface and is expressed on natural killer cells. Recombinant human SIGLEC7, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 64.2kDa (577aa) 70-100kDa (SDS-PAGE under reducing conditions)
- NCBI Accession
- NP_055200
- UniProt
- Q9Y286
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