p53 Protein (AA 133-393) (His tag)

Catalog No. ABIN7424587

Recombinant p53 protein expressed in Escherichia coli (E. coli).

Quick Overview for p53 Protein (AA 133-393) (His tag) (ABIN7424587)

Target: p53 (TP53) (Tumor Protein P53 (TP53))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS), Western Blotting (WB), Immunogen (Imm), Positive Control (PC)

Purity: > 90 %

Product Details

Protein Characteristics: AA 133-393

Purification tag / Conjugate: This p53 protein is labelled with His tag.

Sequence: Met133-Asp393

Characteristics: Recombinant Tumor Protein p53 (P53), Prokaryotic expression, Met133-Asp393, N-terminal His Tag

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Isoelectric Point:8.8

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01 % SKL, 5 % Trehalose and Proclin300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-80 °C

Storage Comment: Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Expiry Date: 12 months

Target Details

Target: p53 (TP53) (Tumor Protein P53 (TP53))

Alternative Name: Tumor Protein p53

Background: TP53, LFS1, TRP53, Li-Fraumeni Syndrome, Cellular tumor antigen p53, Antigen NY-CO-13, Phosphoprotein p53, Tumor suppressor p53

Molecular Weight: 37kDa

UniProt: P04637

Pathways: p53 Signaling, MAPK Signaling, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, Warburg Effect