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p53 Protein (AA 1-393) (GST tag)

Name: p53 Protein (AA 1-393) (GST tag)
SKU: ABIN1323380
Price: 585.71 USD
Availability: InStock

TP53 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

Image no. 1 for Tumor Protein P53 (TP53) (AA 1-393) protein (GST tag) (ABIN1323380) (p53 Protein (AA 1-393) (GST tag))

1 image

(3 references)

Catalog No. ABIN1323380

Datasheet as PDF

Target See all p53 (TP53) Proteins

p53 (TP53) (Tumor Protein P53 (TP53))

Protein Type

Recombinant

Protein Characteristics

AA 1-393
Origin
17

4

4

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

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Human
Source
25

14

4

1

1

1

1

1

1
Wheat germ

Purification tag / Conjugate

This p53 protein is labelled with GST tag.

Application

Western Blotting (WB), ELISA, Affinity Purification (AP), Antibody Array (AA)

Purpose

TP53 (Human) Recombinant Protein (P02)

Sequence

MEEPQSDPSV EPPLSQETFS DLWKLLPENN VLSPLPSQAM DDLMLSPDDI EQWFTEDPGP DEAPRMPEAA PRVAPAPAAP TPAAPAPAPS WPLSSSVPSQ KTYQGSYGFR LGFLHSGTAK SVTCTYSPAL NKMFCQLAKT CPVQLWVDST PPPGTRVRAM AIYKQSQHMT EVVRRCPHHE RCSDSDGLAP PQHLIRVEGN LRVEYLDDRN TFRHSVVVPY EPPEVGSDCT TIHYNYMCNS SCMGGMNRRP ILTIITLEDS SGNLLGRNSF EVRVCACAGR DRRTEEENLR KKGEPHHELP PGSTKRALPN NTSSSPQPKK KPLDGEYFTL QIRGRERFEM FRELNEALEL KDAQAGKEPG GSRAHSSHLK SKKGQSTSRH KKLMFKTEGP DSD

Characteristics

Human TP53 full-length ORF ( AAH03596, 1 a.a. - 393 a.a.) recombinant protein with GST-tag at N-terminal.

Purification

in vitro wheat germ expression system
Tumor Protein P53 (TP53) (Active) protein (His tag)
TP53 Origin: Human Host: Escherichia coli (E. coli) Recombinant STD, PI, in vitro Active

Tumor Protein P53 (TP53) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)
TP53 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining STD, AbP

Tumor Protein P53 (TP53) (AA 1-391) protein (His tag)
TP53 Origin: Rat Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA

Tumor Protein P53 (TP53) (AA 94-201) protein (GST tag)
TP53 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

Tumor Protein P53 (TP53) (AA 1-393) protein (Strep Tag)
Crystallography grade TP53 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA

Tumor Protein P53 (TP53) (AA 1-387) protein (His tag)
Crystallography grade TP53 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys

Tumor Protein P53 (TP53) protein (His-SUMO Tag)
TP53 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90% as determined by SDS-PAGE. ELISA

Tumor Protein P53 (TP53) (AA 1-386) protein (His tag)
TP53 Origin: Cow Host: Escherichia coli (E. coli) Recombinant >95 % as determined by reducing SDS-PAGE.

Tumor Protein P53 (TP53) (AA 1-390) protein (His tag)
TP53 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 97 % WB, SDS, Imm, PC

Tumor Protein P53 (TP53) (AA 90-354) protein (His tag)
TP53 Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 97 % WB, SDS, Imm, PC

Application Notes

Optimal working dilution should be determined by the investigator.

Comment

Preparation method: in vitro, wheat germ expression system
Product Quality tested by: 12.5% SDS-PAGE Stained with Coomassie Blue.

Restrictions

For Research Use only
Buffer

50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.

Handling Advice

Aliquot to avoid repeated freezing and thawing.

Storage

-80 °C

Storage Comment

Best use within three months from the date of receipt of this protein.
Zhang, Zhong, Chen: "LC-MS/MS-based targeted proteomics quantitatively detects the interaction between p53 and MDM2 in breast cancer." in: Journal of proteomics, Vol. 152, pp. 172-180, (2016) (PubMed).

Lacombe, Mangé, Bougnoux, Prassas, Solassol: "A multiparametric serum marker panel as a complementary test to mammography for the diagnosis of node-negative early-stage breast cancer and DCIS in young women." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 23, Issue 9, pp. 1834-42, (2014) (PubMed).

Huang, Jeong, Okamura, Sook-Kim, Zhu, Guerrero-Preston, Ratovitski: "Global tumor protein p53/p63 interactome: making a case for cisplatin chemoresistance." in: Cell cycle (Georgetown, Tex.), Vol. 11, Issue 12, pp. 2367-79, (2012) (PubMed).
Target

p53 (TP53) (Tumor Protein P53 (TP53))

Alternative Name

TP53 (TP53 Products)

Synonyms

BCC7 Protein, LFS1 Protein, P53 Protein, TRP53 Protein, p53 Protein, Trp53 Protein, brp53 Protein, drp53 Protein, etID22686.5 Protein, fb40d06 Protein, wu:fb40d06 Protein, zgc:111919 Protein, Tp53 Protein, bbl Protein, bfy Protein, bhy Protein, p44 Protein, tp53 Protein, Xp53 Protein, TP53 Protein, tumor protein p53 Protein, cellular tumor antigen p53 Protein, transformation related protein 53 Protein, tumor protein p53 L homeolog Protein, TP53 Protein, CpipJ_CPIJ002758 Protein, Tp53 Protein, tp53 Protein, Trp53 Protein, tp53.L Protein

Background

Full Gene Name: tumor protein p53
Synonyms: FLJ92943,LFS1,TRP53,p53

Gene ID

7157

Pathways

p53 Signaling, MAPK Signaling, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, Warburg Effect