alpha Fetoprotein Protein (Fc Tag)
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- Target See all alpha Fetoprotein (AFP) Proteins
- alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This alpha Fetoprotein protein is labelled with Fc Tag.
- Purpose
- Recombinant human AFP protein with C-terminal human Fc tag
- Specificity
- AFP (Arg19-Val609) hFc (Glu99-Ala330)
- Characteristics
- Extracellular Domain Protein
- Purification
- affinity purification
- Purity
- The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product AFP Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with deionized water
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))
- Alternative Name
- AFP (AFP Products)
- Synonyms
- FETA Protein, HPAFP Protein, alpha fetoprotein Protein, alpha-fetoprotein Protein, AFP Protein, Afp Protein
- Background
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Synonymes: AFPD, FETA, HPAFP
Description: This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatocarcinoma and with teratoma, and has prognostic value for managing advanced gastric cancer. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. - Molecular Weight
- predicted molecular mass of 92.6 kDa after removal of the signal peptide.The apparent molecular mass of AFP-hFc is 100-130 kDa due to glycosylation.
- Gene ID
- 174
- UniProt
- P02771
- Pathways
- C21-Steroid Hormone Metabolic Process
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