STING/TMEM173 Protein (Fc Tag)
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- Target See all STING/TMEM173 (TMEM173) Proteins
- STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This STING/TMEM173 protein is labelled with Fc Tag.
- Purpose
- Recombinant human TMEM173 protein with N-terminal Human Fc tag
- Specificity
- HFc (Glu99-Ala330) TMEM173 (Leu139-Ser379)
- Characteristics
- Extracellular Domain Protein
- Purification
- affinity purification
- Purity
- The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product TMEM173 Protein
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Transmembrane Protein 173 (TMEM173) (AA 1-379) protein (rho-1D4 tag)
Crystallography grade TMEM173 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Transmembrane Protein 173 (TMEM173) (AA 147-357) protein (His-IF2DI Tag)TMEM173 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Transmembrane Protein 173 (TMEM173) (AA 137-379) protein (His tag)Crystallography grade TMEM173 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Transmembrane Protein 173 (TMEM173) (AA 136-378) protein (His tag)Crystallography grade TMEM173 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Transmembrane Protein 173 (TMEM173) (AA 1-378) protein (rho-1D4 tag)Crystallography grade TMEM173 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with deionized water
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
- Alternative Name
- TMEM173 (TMEM173 Products)
- Synonyms
- ERIS Protein, MITA Protein, MPYS Protein, NET23 Protein, STING Protein, 2610307O08Rik Protein, Mita Protein, RGD1562552 Protein, transmembrane protein 173 Protein, TMEM173 Protein, Tmem173 Protein
- Background
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Synonymes: ERIS, hMITA, hSTING, MITA, MPYS, NET23, SAVI, STING, STING-beta, TMEM173
Description: This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. - Molecular Weight
- predicted molecular mass of 53.2 kDa after removal of the signal peptide.
- Gene ID
- 340061
- UniProt
- Q86WV6
- Pathways
- Activation of Innate immune Response
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