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ANTXR1 Protein (His tag)

ANTXR1 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Catalog No. ABIN7092772
  • Target See all ANTXR1 Proteins
    ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
    Protein Type
    Recombinant
    Origin
    • 11
    • 3
    • 1
    Human
    Source
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This ANTXR1 protein is labelled with His tag.
    Purpose
    Recombinant human ANTXR1 protein with C-terminal 6xHis tag
    Specificity
    ANTXR1 (Glu33-Ser321) 6xHis tag
    Characteristics
    Extracellular Domain Protein
    Purification
    affinity purification
    Purity
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product ANTXR1 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute with deionized water
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
    Alternative Name
    ANTXR1 (ANTXR1 Products)
    Synonyms
    ANTXR1 Protein, ATR Protein, TEM8 Protein, 2310008J16Rik Protein, 2810405N18Rik Protein, Antrx1 Protein, Tem8 Protein, anthrax toxin receptor 1 Protein, ANTXR1 Protein, Antxr1 Protein
    Background
    Synonymes: ATR
    Description: This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq, Oct 2008]
    Molecular Weight
    predicted molecular mass of 33.2 kDa after removal of the signal peptide. The apparent molecular mass of ANTXR1-His is 35-55 kDa due to glycosylation.
    UniProt
    Q9H6X2
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