GP6 Protein (Fc Tag)
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- Target See all GP6 Proteins
- GP6 (Glycoprotein VI (Platelet) (GP6))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This GP6 protein is labelled with Fc Tag.
- Purpose
- Recombinant Human GP6 with C-terminal human Fc tag
- Specificity
- GP6 (Gln21-Lys267) hFc (Glu99-Ala330)
- Characteristics
- Extracellular Domain Protein
- Purification
- affinity purification
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product GP6 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with deionized water
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- GP6 (Glycoprotein VI (Platelet) (GP6))
- Alternative Name
- GP6 (GP6 Products)
- Synonyms
- BDPLT11 Protein, GPIV Protein, GPVI Protein, 9830166G18Rik Protein, Gm469 Protein, Gpvi Protein, GP6 Protein, glycoprotein VI platelet Protein, glycoprotein 6 (platelet) Protein, glycoprotein VI Protein, platelet glycoprotein VI Protein, GP6 Protein, Gp6 Protein, LOC103346235 Protein
- Background
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Synonymes: BDPLT11
Description: This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] - Molecular Weight
- predicted molecular mass of 53.1 kDa after removal of the signal peptide. The apparent molecular mass of GP6-hFc is 55-100 kDa due to glycosylation.
- UniProt
- Q9HCN6
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