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KIR3DL3 Protein (Fc Tag)

KIR3DL3 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Catalog No. ABIN7121540
  • Target See all KIR3DL3 products
    KIR3DL3 (Killer Cell Immunoglobulin-Like Receptor, three Domains, Long Cytoplasmic Tail, 3 (KIR3DL3))
    Protein Type
    Recombinant
    Origin
    Human
    Source
    • 3
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This KIR3DL3 protein is labelled with Fc Tag.
    Purpose
    Human KIR3DL3 / CD158z Protein, Fc Tag
    Sequence
    Gln 26 - Leu 322
    Characteristics
    Human KIR3DL3, Fc Tag (KI3-H5259) is expressed from human 293 cells (HEK293). It contains AA Gln 26 - Leu 322 (Accession # Q8N743-1).
    Purity
    >95 % as determined by SDS-PAGE.
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
  • Application Notes
    This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 58.7 kDa. The protein migrates as 66 kDa under reducing (R) condition due to glycosylation.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    51 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5
    Storage
    -20 °C
    Storage Comment
    -20°C
  • Target
    KIR3DL3 (Killer Cell Immunoglobulin-Like Receptor, three Domains, Long Cytoplasmic Tail, 3 (KIR3DL3))
    Alternative Name
    KIR3DL3 / CD158z (KIR3DL3 Products)
    Synonyms
    CD158Z Protein, KIR3DL7 Protein, KIR44 Protein, KIRC1 Protein, killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3 Protein, KIR3DL3 Protein
    Background
    Synonyms: Killer cell immunoglobulin-like receptor 3DL3,CD158 antigen-like family member Z,Killer cell inhibitory receptor 1,CD158z,KIR3DL3,KIR3DL7,KIRC1,
    Description: the inhibitory KIR surface receptors possessing three extracellular immunoglobin (Ig) domains (3D) and only one inhibitory motif within the long cytoplasmic domain (L) due to a premature stop codon. Moreover, exon 6 of KIR3DL3 encoding the stem part of the receptor is also absent, which differs from other inhibitory KIRs. Understanding the function of KIR3DL3 is further complicated by the unknown identity of the specific ligand, but its importance is highlighted by its presence in all human KIR haplotypes with 120 distinct polymorphic alleles of the coding sequence [
    Molecular Weight
    58.7 kDa
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