ASXL1 Protein (GST tag)
-
- Target See all ASXL1 Proteins
- ASXL1 (Additional Sex Combs Like 1 (ASXL1))
- Protein Type
- Recombinant
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This ASXL1 protein is labelled with GST tag.
- Purpose
- Recombinant Human ASXL1 Protein (GST Tag)
- Sequence
- Lys1477-Arg154
- Characteristics
- Recombinant Human ASXL1 is produced by our E.coli expression system and the target gene encoding Lys1477-Arg1541 is expressed with a GST tag at the N-terminus.
- Purity
- > 90 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product ASXL1 Protein
-
Additional Sex Combs Like 1 (ASXL1) (AA 1477-1541) protein (His tag)
ASXL1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Additional Sex Combs Like 1 (ASXL1) (AA 1-84) protein (GST tag)ASXL1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Additional Sex Combs Like 1 (ASXL1) (AA 1-1541) protein (Strep Tag)Crystallography grade ASXL1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Additional Sex Combs Like 1 (ASXL1) (AA 1-1514) protein (Strep Tag)Crystallography grade ASXL1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Additional Sex Combs Like 1 (ASXL1) protein (Myc-DYKDDDDK Tag)ASXL1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
- Restrictions
- For Research Use only
-
- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
-
- Target
- ASXL1 (Additional Sex Combs Like 1 (ASXL1))
- Alternative Name
- ASXL1 (ASXL1 Products)
- Synonyms
- asxl1 Protein, MGC83850 Protein, mKIAA0978 Protein, BOPS Protein, MDS Protein, additional sex combs like 1, transcriptional regulator L homeolog Protein, additional sex combs like 1, transcriptional regulator Protein, additional sex combs like 1 Protein, asxl1.L Protein, ASXL1 Protein, asxl1 Protein, Asxl1 Protein
- Background
-
Background: Putative Polycomb group protein ASXL1 involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as retinoic acid receptors (RARs) and peroxisome proliferator-activated receptor gamma (PPARG). It acts as coactivator of RARA and RXRA through association with NCOA1. ASXL1 also acts as corepressor through recruitment of KDM1A and CBX5 to target genes in a cell-type specific manner, the function seems to involve differential recruitment of methylated histone H3 to respective promoters.
Synonym: Putative Polycomb group protein ASXL1, Additional sex combs-like protein 1, ASXL1, KIAA0978,
- Molecular Weight
- 33.6 kDa
- UniProt
- Q8IXJ9
- Pathways
- Retinoic Acid Receptor Signaling Pathway
-
