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AMIGO2 Protein (AA 40-393) (His tag)

AMIGO2 Origin: Human Host: Human Cells Recombinant > 90 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7319701
  • Target See all AMIGO2 Proteins
    AMIGO2 (Adhesion Molecule with Ig-Like Domain 2 (AMIGO2))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 40-393
    Origin
    • 6
    • 4
    • 1
    • 1
    Human
    Source
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This AMIGO2 protein is labelled with His tag.
    Purpose
    Recombinant Human AMIGO2 Protein (aa 40-393, His Tag)
    Sequence
    Val40-His393
    Characteristics
    Recombinant Human AMIGO2 is produced by our Mammalian expression system and the target gene encoding Val40-His393 is expressed with a 6His tag at the C-terminus.
    Purity
    > 90 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
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    Discover our top product AMIGO2 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    AMIGO2 (Adhesion Molecule with Ig-Like Domain 2 (AMIGO2))
    Alternative Name
    AMIGO2 (AMIGO2 Products)
    Synonyms
    AMIGO2 Protein, AI415330 Protein, AMIGO-2 Protein, AW208913 Protein, Ali1 Protein, ALI1 Protein, DEGA Protein, adhesion molecule with Ig like domain 2 Protein, adhesion molecule with Ig-like domain 2 Protein, AMIGO2 Protein, Amigo2 Protein
    Background

    Background: Amphoterin-Induced Protein 2 (AMIGO2) is a single-pass type I membrane protein which belongs to the AMIGO family of immunoglobulin superfamily. Mature AMIGO2 contains an Ig-like C2-type (immunoglobulin-like) domain, 6 LRR (leucine-rich) repeats, a LRRCT domain, as well as a LRRNT domain. AMIGO2 is mainly expressed in in breast, ovary, cervix, and uterus, although lower in lung, colon, and rectum. AMIGO2 required for depolarization-dependent survival of cultured cerebellar granule neurons. AMIGO2 may mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. AMIGO2 may contribute to signal transduction through its intracellular domain, and may be required for tumorigenesis of a subset of gastric adenocarcinomas.

    Synonym: Amphoterin-Induced Protein 2, AMIGO-2, Alivin-1, Differentially Expressed in Gastric Adenocarcinomas, DEGA, ALI1

    Molecular Weight
    41.34 kDa
    UniProt
    Q86SJ2
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