AMIGO2 Protein (AA 40-393) (His tag)
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- Target See all AMIGO2 Proteins
- AMIGO2 (Adhesion Molecule with Ig-Like Domain 2 (AMIGO2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 40-393
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This AMIGO2 protein is labelled with His tag.
- Purpose
- Recombinant Human AMIGO2 Protein (aa 40-393, His Tag)
- Sequence
- Val40-His393
- Characteristics
- Recombinant Human AMIGO2 is produced by our Mammalian expression system and the target gene encoding Val40-His393 is expressed with a 6His tag at the C-terminus.
- Purity
- > 90 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product AMIGO2 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- AMIGO2 (Adhesion Molecule with Ig-Like Domain 2 (AMIGO2))
- Alternative Name
- AMIGO2 (AMIGO2 Products)
- Synonyms
- AMIGO2 Protein, AI415330 Protein, AMIGO-2 Protein, AW208913 Protein, Ali1 Protein, ALI1 Protein, DEGA Protein, adhesion molecule with Ig like domain 2 Protein, adhesion molecule with Ig-like domain 2 Protein, AMIGO2 Protein, Amigo2 Protein
- Background
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Background: Amphoterin-Induced Protein 2 (AMIGO2) is a single-pass type I membrane protein which belongs to the AMIGO family of immunoglobulin superfamily. Mature AMIGO2 contains an Ig-like C2-type (immunoglobulin-like) domain, 6 LRR (leucine-rich) repeats, a LRRCT domain, as well as a LRRNT domain. AMIGO2 is mainly expressed in in breast, ovary, cervix, and uterus, although lower in lung, colon, and rectum. AMIGO2 required for depolarization-dependent survival of cultured cerebellar granule neurons. AMIGO2 may mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. AMIGO2 may contribute to signal transduction through its intracellular domain, and may be required for tumorigenesis of a subset of gastric adenocarcinomas.
Synonym: Amphoterin-Induced Protein 2, AMIGO-2, Alivin-1, Differentially Expressed in Gastric Adenocarcinomas, DEGA, ALI1
- Molecular Weight
- 41.34 kDa
- UniProt
- Q86SJ2
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