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ALDH1A2 Protein (His tag)

ALDH1A2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7318142
  • Target See all ALDH1A2 Proteins
    ALDH1A2 (Aldehyde Dehydrogenase 1 Family, Member A2 (ALDH1A2))
    Protein Type
    Recombinant
    Origin
    • 7
    • 1
    • 1
    Human
    Source
    • 3
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This ALDH1A2 protein is labelled with His tag.
    Purpose
    Recombinant Human ALDH1A2 Protein (His Tag)
    Sequence
    Met 1-Ser518
    Characteristics
    Recombinant Human Aldehyde dehydrogenase family 1 member A2 is produced by our E.coli expression system and the target gene encoding Met1-Ser518 is expressed with a 6His tag at the N-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product ALDH1A2 Protein
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,150 mMNaCl, pH 7.5,20 % Glycerol.
    Storage
    -20 °C
    Storage Comment
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    ALDH1A2 (Aldehyde Dehydrogenase 1 Family, Member A2 (ALDH1A2))
    Alternative Name
    ALDH1A2 (ALDH1A2 Products)
    Synonyms
    Raldh-2 Protein, RALDH(II) Protein, RALDH2 Protein, RALDH2-T Protein, fb50h01 Protein, raldh2 Protein, AV116159 Protein, Aldh1a7 Protein, Raldh1 Protein, Raldh2 Protein, aldehyde dehydrogenase 1 family, member A2 Protein, aldehyde dehydrogenase 1 family member A2 Protein, aldehyde dehydrogenase family 1, subfamily A2 Protein, Aldh1a2 Protein, ALDH1A2 Protein, aldh1a2 Protein
    Background

    Background: Aldehyde dehydrogenase 1 family member A2 (ALDH1A2), also known as retinaldehyde dehydrogenase 2 (RALDH2), belongs to the aldehyde dehydrogenase family which contains two members, the ALDH1 s (ALDH1A1, ALDH1A2 and ALDH1A3) and the 9-cis retinaldehyde dehydrogenase ALDH8 s. ALDH1A2 is key enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. RA is a paracrine hormone signaling molecule that functions in developing and adult tissues. ALDH1A2 was also found to regulate normal and tumor cell growth and differentiation. Several studies showed that ALDH1A2 expression is increased after the appearance of AraC resistance in clinical cases which means this protein is effective in AraC resistance.

    Synonym: Aldehyde dehydrogenase family 1 member A2, Retinaldehyde-specific dehydrogenase type 2, RALDH(II), Retinal dehydrogenase 2, ALDH1A2, RALDH2

    Molecular Weight
    58.2 kDa
    UniProt
    O94788
    Pathways
    Retinoic Acid Receptor Signaling Pathway
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