ALDH1A3 Protein (His tag)
-
- Target See all ALDH1A3 Proteins
- ALDH1A3 (Aldehyde Dehydrogenase 1 Family, Member A3 (ALDH1A3))
- Protein Type
- Recombinant
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This ALDH1A3 protein is labelled with His tag.
- Purpose
- Recombinant Human ALDH1A3 Protein (His Tag)
- Sequence
- Met1-Pro512
- Characteristics
- Recombinant Human ALDH1A3 is produced by our E.coli expression system and the target gene encoding Met1-Pro512 is expressed with a 6His tag at the N-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product ALDH1A3 Protein
-
-
- Restrictions
- For Research Use only
-
- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,150 mMNaCl, pH 7.5,20 % Glycerol.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
-
- Target
- ALDH1A3 (Aldehyde Dehydrogenase 1 Family, Member A3 (ALDH1A3))
- Alternative Name
- ALDH1A3 (ALDH1A3 Products)
- Synonyms
- RALDH3 Protein, ALDH1A3 Protein, ALDH1A6 Protein, ALDH6 Protein, MCOP8 Protein, Aldh6 Protein, V1 Protein, aldehyde dehydrogenase 1 family member A3 Protein, aldehyde dehydrogenase 1 family member A3 L homeolog Protein, aldehyde dehydrogenase 1 family, member A3 Protein, aldehyde dehydrogenase family 1, subfamily A3 Protein, ALDH1A3 Protein, aldh1a3.L Protein, aldh1a3 Protein, Aldh1a3 Protein
- Background
-
Background: Aldehyde dehydrogenase 1 family member A3 (ALDH1A3), also known as retinaldehyde dehydrogenase 3 (RALDH3), is a member of the aldehyde dehydrogenase family known to metabolize a wide variety of aldehydes. ALDH1A3 specifically oxidizes retinal to retinoic acid (RA) and is differentially expressed in developing embryonic tissues and adult organs. The RA produced by ALDH1A3 in rodents contributes to the development of skin and hair follicles, brain, tooth buds, lungs, olfactory bulbs, kidneys, eyes, skeletal muscle and seminal vesicles. In recent research, ALDH1A3 could be as a marker of cancer stem cell to predict metastasis or clinical prognosis in many cancers.
Synonym: Aldehyde dehydrogenase family 1 member A3, ALDH1A3, Aldehyde dehydrogenase 6, Retinaldehyde dehydrogenase 3, RALDH-3, ALDH6,ALDH1A6,MCOP8,RALDH3
- Molecular Weight
- 57.5 kDa
- UniProt
- P47895
- Pathways
- Retinoic Acid Receptor Signaling Pathway
-
