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APLP1 Protein (AA 1-580) (His tag)

APLP1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7317207
  • Target See all APLP1 Proteins
    APLP1 (Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-580
    Origin
    • 6
    • 4
    Human
    Source
    • 4
    • 3
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This APLP1 protein is labelled with His tag.
    Purpose
    Recombinant Human APLP-1 Protein (aa 1-580, His Tag)
    Sequence
    Met 1-Glu580
    Characteristics
    A DNA sequence encoding the human APLP1 (P51693-1) (Met1-Glu580) was expressed with a polyhistidine tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product APLP1 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile PBS, PH 7.4
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    APLP1 (Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))
    Alternative Name
    APLP-1 (APLP1 Products)
    Synonyms
    aplp Protein, MGC115336 Protein, APLP Protein, Aplp1_retired Protein, RGD1561211 Protein, amyloid beta precursor like protein 1 Protein, amyloid beta precursor like protein 1 L homeolog Protein, amyloid beta (A4) precursor-like protein 1 Protein, APLP1 Protein, aplp1.L Protein, aplp1 Protein, Aplp1 Protein
    Background

    Background: APLP1, also known as amyloid-like protein 1, is a member of the highly conserved amyloid precursor protein gene family. APLP1 is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. APLP1, together with APLP2, are important modulators of glucose. APLP1 may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. APLP1 also is a mammalian homologue of amyloid precursor protein (APP). APP is a type I membrane protein that is genetically linked to Alzheimer's disease.

    Synonym: Amyloid-like protein 1, APLP, APLP-1, C30, APLP1

    Molecular Weight
    61.9 kDa
    Pathways
    cAMP Metabolic Process
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