APLP1 Protein (His tag)
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- Target See all APLP1 Proteins
- APLP1 (Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This APLP1 protein is labelled with His tag.
- Purpose
- Recombinant Human APLP-1 Protein
- Sequence
- SLAGGSPGAA EAPGSAQVAG LCGRLTLHRD LRTGRWEPDP QRSRRCLRDP QRVLEYCRQM YPELQIARVE QATQAIPMER WCGGSRSGSC AHPHHQVVPF RCLPGEFVSE ALLVPEGCRF LHQERMDQCE SSTRRHQEAQ EACSSQGLIL HGSGMLLPCG SDRFRGVEYV CCPPPGTPDP SGTAVGDPST RSWPPGSRVE GAEDEEEEES FPQPVDDYFV EPPQAEEEEE TVPPPSSHTL AVVGKVTPTP RPTDGVDIYF GMPGEISEHE GFLRAKMDLE ERRMRQINEV MREWAMADNQ SKNLPKADRQ ALNEHFQSIL QTLEEQVSGE RQRLVETHAT RVIALINDQR RAALEGFLAA LQADPPQAER VLLALRRYLR AEQKEQRHTL RHYQHVAAVD PEKAQQMRFQ VHTHLQVIEE RVNQSLGLLD QNPHLAQELR PQIQELLHSE HLGPSELEAP APGGSSEDKG GLQPPDSKDD TPMTLPKGST EQDAASPEKE KMNPLEQYER KVNASVPRGF PFHSSEIQRD ELAPAGTGVS RE
- Specificity
- Ser39-Glu580
- Purity
- > 95 % by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- <0.1EU/μg
- Top Product
- Discover our top product APLP1 Protein
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Amyloid beta (A4) Precursor-Like Protein 1 (APLP1) (AA 523-625) protein (GST tag)
APLP1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Amyloid beta (A4) Precursor-Like Protein 1 (APLP1) (AA 39-580) protein (His tag)Crystallography grade APLP1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Amyloid beta (A4) Precursor-Like Protein 1 (APLP1) (AA 38-583) protein (His tag)Crystallography grade APLP1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Amyloid beta (A4) Precursor-Like Protein 1 (APLP1) (AA 39-650) protein (rho-1D4 tag)Crystallography grade APLP1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Amyloid beta (A4) Precursor-Like Protein 1 (APLP1) (AA 38-653) protein (rho-1D4 tag)Crystallography grade APLP1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- Buffer
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store the lyophilized protein at -20°C to -80°C for long term.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
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- Target
- APLP1 (Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))
- Alternative Name
- APLP-1 (APLP1 Products)
- Synonyms
- aplp Protein, MGC115336 Protein, APLP Protein, Aplp1_retired Protein, RGD1561211 Protein, amyloid beta precursor like protein 1 Protein, amyloid beta precursor like protein 1 L homeolog Protein, amyloid beta (A4) precursor-like protein 1 Protein, APLP1 Protein, aplp1.L Protein, aplp1 Protein, Aplp1 Protein
- Background
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Description: APLP1, also known as amyloid-like protein 1, is a member of the highly conserved amyloid precursor protein gene family. APLP1 is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. APLP1, together with APLP2, are important modulators of glucose. APLP1 may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. APLP1 also is a mammalian homologue of amyloid precursor protein (APP). APP is a type I membrane protein that is genetically linked to Alzheimer's disease.
Name: APLP1,APLP
- Gene ID
- 333
- UniProt
- P51693
- Pathways
- cAMP Metabolic Process
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