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APCS Protein (His tag)

APCS Origin: Rat Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
Catalog No. ABIN7321229
  • Target See all APCS Proteins
    APCS (Amyloid P Component, Serum (APCS))
    Protein Type
    Recombinant
    Origin
    • 13
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    Rat
    Source
    • 8
    • 6
    • 5
    • 4
    • 3
    HEK-293 Cells
    Purification tag / Conjugate
    This APCS protein is labelled with His tag.
    Purpose
    Recombinant Rat APCS/SAP Protein (His Tag)
    Sequence
    Met 1-Ser 228
    Characteristics
    A DNA sequence encoding the rat APCS (P23680) (Met 1-Ser 228) was expressed, fused with a polyhistidine tag at the C-terminus.
    Purity
    > 95 % as determined by SDS-PAGE
    Endotoxin Level
    < 1.0 EU per μg of the protein as determined by the LAL method
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    Discover our top product APCS Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile PBS, pH 7.4
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    APCS (Amyloid P Component, Serum (APCS))
    Alternative Name
    APCS/SAP (APCS Products)
    Synonyms
    PTX2 Protein, SAP Protein, Sap Protein, APCS Protein, FP Protein, SAP(FP) Protein, apcs Protein, ptx2 Protein, sap Protein, amyloid P component, serum Protein, serum amyloid P-component Protein, amyloid P component, serum protein L homeolog Protein, APCS Protein, Apcs Protein, apcs.L Protein
    Background

    Background: Serum amyloid P component (SAP) is the identical serum form of amyloid P component (AP), a highly preserved plasma protein named for its ubiquitous presence in amyloid deposits. As a normal plasma protein first identified as the pentagonal constituent of in vivo pathological deposits called "amyloid". Serum amyloid P component represents another member of the pentraxin family, a highly conserved group of molecules that may play a role in innate immunity. SAP is a key negative regulator for innate immune responses to DNA and may be partly responsible for the insufficient immune responses after DNA vaccinations in humans. SAP suppression may be a novel strategy for improving efficacy of human DNA vaccines and requires further clinical investigations.

    Synonym: Sap

    Molecular Weight
    25.3 kDa
    UniProt
    P23680
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