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APCS Products

(Amyloid P Component, Serum (APCS))
The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo. [provided by RefSeq, Sep 2008].

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Featured APCS Categories

APCS Antibodies

High quality antibodies with extensive validation data.

APCS ELISA Kits

Reliable ELISA kits for a wide range of species.

APCS Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended APCS Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (7)
Cat. No. ABIN7438559
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (7)
Cat. No. ABIN7433756
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (6)
Cat. No. ABIN3022714
Quantity 100 μL
Datasheet Datasheet

Recommended APCS ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (4)
  • (1)
Cat. No. ABIN6953696
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6953697
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN7041556
Quantity 96 tests
Datasheet Datasheet

Recommended APCS Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275546
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275545
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1345301
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our APCS products

Musilova, Andrys, Krejsek, Drahosova, Zednikova, Pliskova, Zemlickova, Jacobsson, Kacerovsky: "Amniotic fluid pentraxins: Potential early markers for identifying intra-amniotic inflammatory complications in preterm pre-labor rupture of membranes." in: American journal of reproductive immunology (New York, N.Y. : 1989), Vol. 79, Issue 5, pp. e12789, (2019) (PubMed).

Ferrín, Ranchal, Llamoza, Rodríguez-Perálvarez, Romero-Ruiz, Aguilar-Melero, López-Cillero, Briceño, Muntané, Montero-Álvarez, De la Mata: "Identification of candidate biomarkers for hepatocellular carcinoma in plasma of HCV-infected cirrhotic patients by 2-D DIGE." in: Liver international : official journal of the International Association for the Study of the Liver, Vol. 34, Issue 3, pp. 438-46, (2015) (PubMed).

Sponarova, Nuvolone, Whicher, Frei, Kana, Schwarz, Westermark, Aguzzi: "Efficient amyloid A clearance in the absence of immunoglobulins and complement factors." in: The American journal of pathology, Vol. 182, Issue 4, pp. 1297-307, (2013) (PubMed).

Ramos-Sevillano, Rodríguez-Sosa, Cafini, Giménez, Navarro, Sevillano, Alou, García, Aguilar, Yuste: "Cefditoren and ceftriaxone enhance complement-mediated immunity in the presence of specific antibodies against antibiotic-resistant pneumococcal strains." in: PLoS ONE, Vol. 7, Issue 9, pp. e44135, (2012) (PubMed).

Oberbach, Blüher, Wirth, Till, Kovacs, Kullnick, Schlichting, Tomm, Rolle-Kampczyk, Murugaiyan, Binder, Dietrich, von Bergen: "Combined proteomic and metabolomic profiling of serum reveals association of the complement system with obesity and identifies novel markers of body fat mass changes." in: Journal of proteome research, Vol. 10, Issue 10, pp. 4769-88, (2011) (PubMed).

Maher, Dargusch, Ehren, Okada, Sharma, Schubert: "Fisetin lowers methylglyoxal dependent protein glycation and limits the complications of diabetes." in: PLoS ONE, Vol. 6, Issue 6, pp. e21226, (2011) (PubMed).

Ma, Luo, Wu, Chen, Kou, Wang: "Circulation levels of acute phase proteins in patients with Takayasu arteritis." in: Journal of vascular surgery, Vol. 51, Issue 3, pp. 700-6, (2010) (PubMed).

Veerhuis, Boshuizen, Morbin, Mazzoleni, Hoozemans, Langedijk, Tagliavini, Langeveld, Eikelenboom: "Activation of human microglia by fibrillar prion protein-related peptides is enhanced by amyloid-associated factors SAP and C1q." in: Neurobiology of disease, Vol. 19, Issue 1-2, pp. 273-82, (2005) (PubMed).

Maeda: "Use of genetically altered mice to study the role of serum amyloid P component in amyloid deposition." in: Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis, Vol. 10 Suppl 1, pp. 17-20, (2003) (PubMed).

Hawkins: "Serum amyloid P component scintigraphy for diagnosis and monitoring amyloidosis." in: Current opinion in nephrology and hypertension, Vol. 11, Issue 6, pp. 649-55, (2002) (PubMed).

Synonyms and alternative names related to APCS

amyloid P component, serum (APCS), amyloid P component, serum (Apcs), serum amyloid P-component (Apcs), amyloid P component, serum protein L homeolog (apcs.L), APCS, apcs, FP, PTX2, ptx2, SAP, Sap, sap, SAP(FP)

Protein level used designations for APCS

  • 9.5S alpha-1-glycoprotein
  • pentaxin-related
  • serum amyloid P-component
  • serum amyloid P component
  • amyloid P component, serum
  • SAP
  • pentraxin
  • C-reactive protein
  • amyloid P component serum
  • APCS amyloid P-component serum protein
  • Serum amyloid P-component
  • LOW QUALITY PROTEIN: serum amyloid P-component
  • Female protein
  • amyloid P component, serum protein L homeolog
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