BCL6 Protein (AA 1-150) (TRX tag,His tag)
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- Target See all BCL6 Proteins
- BCL6 (B-Cell CLL/lymphoma 6 (BCL6))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-150
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This BCL6 protein is labelled with TRX tag,His tag.
- Purpose
- Recombinant Human BCL6/B-cell CLL lymphoma 6 Protein (aa 1-150, His & Trx Tag)
- Sequence
- Met 1-Met 150
- Characteristics
- A DNA sequence encoding the human BCL6 (P41182) N-terminal fragment (Met 1-Met 150) was fused with a Trx and a polyhistidine tag at the N-terminus.
- Purity
- > 92 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product BCL6 Protein
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B-Cell CLL/lymphoma 6 (BCL6) (AA 1-174) protein (His-IF2DI Tag)
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B-Cell CLL/lymphoma 6 (BCL6) (AA 1-706) protein (Strep Tag)Crystallography grade BCL6 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
B-Cell CLL/lymphoma 6 (BCL6) (AA 1-707) protein (Strep Tag)Crystallography grade BCL6 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
B-Cell CLL/lymphoma 6 (BCL6) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)BCL6 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile 20 mM Tris, 10 % glycerol, pH 8.0
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- BCL6 (B-Cell CLL/lymphoma 6 (BCL6))
- Alternative Name
- BCL6/B-cell CLL lymphoma 6 (BCL6 Products)
- Synonyms
- bcl5 Protein, laz3 Protein, bcl6a Protein, znf51 Protein, zbtb27 Protein, MGC132260 Protein, Bcl5 Protein, BCL5 Protein, BCL6A Protein, LAZ3 Protein, ZBTB27 Protein, ZNF51 Protein, B-cell CLL/lymphoma 6 L homeolog Protein, B-cell CLL/lymphoma 6 Protein, B cell leukemia/lymphoma 6 Protein, bcl6.L Protein, bcl6 Protein, BCL6 Protein, Bcl6 Protein
- Background
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Background: The protein encoded by this gene is an evolutionarily conserved 95-kDa protein containing six C-terminal zinc-finger motifs and an N-terminal POZ domain. It has been reported that BCL-6 is present in DNA-binding complexes in nuclear extracts from various B-cell lines. There are many relationships between non-Hodgkin's lymphoma, diffuse large cell lymphoma and BCL6’s translocations. BCL6 can repress transcription from promoters linked to its DNA target sequence and this activity is dependent upon specific DNA-binding and the presence of an intact N-terminal half of the protein.
Synonym: BCL5;BCL6A;LAZ3;ZBTB27;ZNF51
- Molecular Weight
- 34.2 kDa
- UniProt
- P41182
- Pathways
- Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
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