Biglycan Protein (BGN) (His tag)
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- Target See all Biglycan (BGN) Proteins
- Biglycan (BGN)
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This Biglycan protein is labelled with His tag.
- Purpose
- Recombinant Human Biglycan/BGN Protein (His Tag)
- Sequence
- Glu20-Lys368
- Characteristics
- Recombinant Human Biglycan is produced by our Mammalian expression system and the target gene encoding Glu20-Lys368 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product BGN Protein
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Biglycan (BGN) (AA 1-368) protein (GST tag)
BGN Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Biglycan (BGN) protein (Fc Tag)BGN Origin: Mouse Host: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE
Biglycan (BGN) (AA 38-368) protein (His tag)Crystallography grade BGN Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Biglycan (BGN) (AA 38-369) protein (His tag)Crystallography grade BGN Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- Biglycan (BGN)
- Alternative Name
- Biglycan/BGN (BGN Products)
- Synonyms
- DSPG1 Protein, PG-S1 Protein, PGI Protein, SLRR1A Protein, BG Protein, BSPG1 Protein, bgn Protein, zgc:91989 Protein, dspg1 Protein, pg-s1 Protein, slrr1a Protein, xbgn Protein, BGN Protein, zgc:77123 Protein, DKFZp468I2427 Protein, biglycan Protein, biglycan L homeolog Protein, biglycan a Protein, biglycan S homeolog Protein, biglycan b Protein, BGN Protein, Bgn Protein, bgn.L Protein, bgna Protein, bgn.S Protein, bgn Protein, bgnb Protein
- Background
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Background: Biglycan is a 200-350 kD proteoglycan consisting of a 45 kD core protein and two chrondroitin/dermatan sulfate glycosaminoglycan chains. Biglycan binds to TGF-?. It also binds to collagen type I in low ionic strength (less than 3 mM phosphate) buffer. At higher ionic strengths, Biglycan does not bind to collagen type I. It enhances the inhibition effect of TGF-? on osteoclast proliferation at a concentration of 4-20 mg/mL. It also prevents the attachment of CHO cells to fibronectin, with a 50 % inhibition at 17-21 mg/mL.
Synonym: Biglycan, Bone/Cartilage Proteoglycan I, PG-S1, BGN, SLRR1A
- Molecular Weight
- 40.5 kDa
- UniProt
- P21810
- Pathways
- Glycosaminoglycan Metabolic Process
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