BDNF Protein (AA 19-247)
Quick Overview for BDNF Protein (AA 19-247) (ABIN7319494)
Target
See all BDNF ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 19-247
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Purpose
- Recombinant Human BDNF Protein (with pro peptide)
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Sequence
- Ala19-Arg247(R125A,R127A,R128A)
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Characteristics
- Recombinant Human BDNF is produced by our E.coli expression system and the target gene encoding Ala19-Arg247 is expressed.
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Brain-Derived Neurotrophic Factor (BDNF) (Active) protein (Biotin)
BDNF Origin: Human Host: Escherichia coli (E. coli) Recombinant WB, CC, in vivo, Diff, CyTox, AD, FM, IF, LCI Active
Brain-Derived Neurotrophic Factor (BDNF) (AA 1-255) protein (GST tag)BDNF Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Brain-Derived Neurotrophic Factor (BDNF) (AA 1-247) protein (GST tag)BDNF Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Brain-Derived Neurotrophic Factor (BDNF) proteinBDNF Origin: Human Host: Escherichia coli (E. coli) Recombinant 97,00% SDS
Brain-Derived Neurotrophic Factor (BDNF) (AA 137-237), (partial) protein (GST tag)BDNF Origin: Human Host: Escherichia coli (E. coli) Recombinant 90 % SDS, ELISA
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM PB, 10 % Trehalose, 100 mM NaCl, 0.02 % Tween 80, pH 6.0.
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Storage
- -20 °C
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Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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Expiry Date
- 6 months
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- BDNF (Brain-Derived Neurotrophic Factor (BDNF))
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Alternative Name
- BDNF
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Background
- Abrineurin,BDNF,Brain-Derived Neurotrophic Factor,The precursor form of Brain-Derived Neurotrophic Factor (pro-BDNF) interacts preferentially with the pan-neurotrophin receptor p75 (p75NTR) and vps10p domain-containing receptor sortilin and induces neuronal apoptosis, whereas mature BDNF selectively binds with high affinity to the TrkB kinase receptor and promotes the survival, growth and differentiation of neurons. As proneurotrophins and mature neurotrophins elicit opposite biological effects, Pro-BDNF cleavage in the neuronal system is regulated in a specific and cell-context dependent manner. Pro-BDNF plays important role in negative regulation of neurotrophic actions in the brain.
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Molecular Weight
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Calculated MW: 25.6 kDa
Observed MW: 28 kDa
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Gene ID
- 627
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UniProt
- P23560
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Pathways
- RTK Signaling, Synaptic Membrane, Feeding Behaviour, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity
Target
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