BAI3 Protein (His tag)
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- Target See all BAI3 Proteins
- BAI3 (Brain-Specific Angiogenesis Inhibitor 3 (BAI3))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This BAI3 protein is labelled with His tag.
- Purpose
- Recombinant Human BAI3 Protein (His Tag)
- Sequence
- Ala25-Thr880
- Characteristics
- Recombinant Human Brain-Specific Angiogenesis Inhibitor 3 is produced by our Mammalian expression system and the target gene encoding Ala25-Thr880 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product BAI3 Protein
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Brain-Specific Angiogenesis Inhibitor 3 (BAI3) (AA 26-135) protein (GST tag)
BAI3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 5 % Thehalose, pH 7.2.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- BAI3 (Brain-Specific Angiogenesis Inhibitor 3 (BAI3))
- Alternative Name
- BAI3 (BAI3 Products)
- Synonyms
- zgc:163001 Protein, BAI3 Protein, A830096D10Rik Protein, adhesion G protein-coupled receptor B3 Protein, brain-specific angiogenesis inhibitor 3 Protein, ADGRB3 Protein, Adgrb3 Protein, adgrb3 Protein, BAI3 Protein
- Background
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Background: Human Brain-Specific Angiogenesis Inhibitor 3 (BAI3) is a 177 kDa seven-span transmembrane (TM) protein, which is thought to be a member of the secretin receptor family. It is synthesized by neurons of the CNS and likely is a negative regulator of angiogenesis. BAI3 is 1498 amino acids in size. It contains three distinct regions: an N-terminal extracellular domain (ECD) (aa25-883), a 7-TM segment, and a C-terminal cytoplasmic region. The ECD contains four antiangiogenic TSP type 1 repeat (aa296-508), and one GSP domain (aa 816-867) that is likely used to cleave the ECD from the membrane-bound receptor. There is one altermate splice form that shows a deletion of aa 643-665. Over aa 25-880, human BAI3 shares 98 % aa identity with mouse BAI3. BAI3 has been reported primarily in the brain, but is also localized to lung, testis, and pancreas. It might be involved in angiogenesis inhibition and suppression of glioblastoma.
Synonym: Brain-Specific Angiogenesis Inhibitor 3, BAI3, KIAA0550
- Molecular Weight
- 97.5 kDa
- UniProt
- O60242
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