CLEC10A Protein (Fc Tag)
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- Target See all CLEC10A Proteins
- CLEC10A (C-Type Lectin Domain Family 10, Member A (CLEC10A))
- Protein Type
- Recombinant
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CLEC10A protein is labelled with Fc Tag.
- Purpose
- Recombinant Mouse CLEC10A/CD301 Protein (Fc Tag)
- Sequence
- Gln 58-Ser 305
- Characteristics
- A DNA sequence encoding the extracellular domain of mouse CLEC10A (NP_001191181.1) (Gln 58-Ser 305) was fused with the Fc region of human IgG1 at the N-terminus.
- Purity
- > 86 % as determined by SDS-PAGE
- Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Top Product
- Discover our top product CLEC10A Protein
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C-Type Lectin Domain Family 10, Member A (CLEC10A) (AA 57-304) protein (His tag)
CLEC10A Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
C-Type Lectin Domain Family 10, Member A (CLEC10A) (AA 61-316) protein (His tag)CLEC10A Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
C-Type Lectin Domain Family 10, Member A (CLEC10A) (AA 61-292) protein (His tag)CLEC10A Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
C-Type Lectin Domain Family 10, Member A (CLEC10A) (AA 1-316) protein (GST tag)CLEC10A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
C-Type Lectin Domain Family 10, Member A (CLEC10A) (AA 70-169) protein (GST tag)CLEC10A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
C-Type Lectin Domain Family 10, Member A (CLEC10A) (AA 61-316) protein (His tag)Crystallography grade CLEC10A Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
C-Type Lectin Domain Family 10, Member A (CLEC10A) (AA 57-304) protein (His tag)Crystallography grade CLEC10A Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
C-Type Lectin Domain Family 10, Member A (CLEC10A) (AA 1-316) protein (Strep Tag)Crystallography grade CLEC10A Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
C-Type Lectin Domain Family 10, Member A (CLEC10A) (AA 1-304) protein (Strep Tag)Crystallography grade CLEC10A Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- CLEC10A (C-Type Lectin Domain Family 10, Member A (CLEC10A))
- Alternative Name
- CLEC10A/CD301 (CLEC10A Products)
- Synonyms
- CLEC10A Protein, CD301 Protein, CLECSF13 Protein, CLECSF14 Protein, HML Protein, HML2 Protein, MGL Protein, CD301a Protein, M-ASGP-BP-1 Protein, Mgl Protein, Mgl1 Protein, Mgll Protein, C-type lectin domain family 10 member A Protein, C-type lectin domain containing 10A Protein, C-type lectin domain family 10, member A Protein, LOC607405 Protein, CLEC10A Protein, Clec10a Protein
- Background
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Background: CLEC10A, also known as the macrophage galactose-type calcium-type lectins (MGLs, CD301) constitute a unique class of C-type lectins because of their specificity for galactose and its structural homologues. MGLs/CD301 is a type II transmembrane glycoproteins and is expressed on macrophages and related cells of myeloid origins, particularly immature dendritic cells (DCs). There are 2 homologues: MGL1 and MGL2 (CD301a and CD301b) in mice. MGL1/CD301a induces both the production and secretion of interleukin (IL)-10. MGL1/CD301a plays a protective role against colitis by effectively inducing IL-10 production by colonic lamina propria macrophages in response to invading commensal bacteria.
Synonym: CD301a,M-ASGP-BP-1,Mgl,Mgl1
- Molecular Weight
- 56.7 kDa
- NCBI Accession
- NP_001191181
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