CLEC10A Protein (His tag)
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- Target See all CLEC10A Proteins
- CLEC10A (C-Type Lectin Domain Family 10, Member A (CLEC10A))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CLEC10A protein is labelled with His tag.
- Purpose
- Recombinant Human CD301 Protein
- Sequence
- QNSKFQRDLV TLRTDFSNFT SNTVAEIQAL TSQGSSLEET IASLKAEVEG FKQERQAGVS ELQEHTTQKA HLGHCPHCPS VCVPVHSEML LRVQQLVQDL KKLTCQVATL NNNASTEGTC CPVNWVEHQD SCYWFSHSGM SWAEAEKYCQ LKNAHLVVIN SREEQNFVQK YLGSAYTWMG LSDPEGAWKW VDGTDYATGF QNWKPGQPDD WQGHGLGGGE DCAHFHPDGR WNDDVCQRPY HWVCEAGLGQ TSQESH
- Specificity
- Gln61-His316
- Purity
- > 90 % by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- < 1.0 EU/μg of the protein by LAL method.
- Top Product
- Discover our top product CLEC10A Protein
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C-Type Lectin Domain Family 10, Member A (CLEC10A) (AA 57-304) protein (His tag)
CLEC10A Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
C-Type Lectin Domain Family 10, Member A (CLEC10A) (AA 61-316) protein (His tag)CLEC10A Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
C-Type Lectin Domain Family 10, Member A (CLEC10A) (AA 61-292) protein (His tag)CLEC10A Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
C-Type Lectin Domain Family 10, Member A (CLEC10A) (AA 1-316) protein (GST tag)CLEC10A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
C-Type Lectin Domain Family 10, Member A (CLEC10A) (AA 70-169) protein (GST tag)CLEC10A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
C-Type Lectin Domain Family 10, Member A (CLEC10A) protein (Fc Tag)CLEC10A Origin: Mouse Host: HEK-293 Cells Recombinant > 86 % as determined by SDS-PAGE
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- Buffer
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- Storage
- -20 °C,-80 °C
- Storage Comment
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Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
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- Target
- CLEC10A (C-Type Lectin Domain Family 10, Member A (CLEC10A))
- Alternative Name
- CD301 (CLEC10A Products)
- Synonyms
- CLEC10A Protein, CD301 Protein, CLECSF13 Protein, CLECSF14 Protein, HML Protein, HML2 Protein, MGL Protein, CD301a Protein, M-ASGP-BP-1 Protein, Mgl Protein, Mgl1 Protein, Mgll Protein, C-type lectin domain family 10 member A Protein, C-type lectin domain containing 10A Protein, C-type lectin domain family 10, member A Protein, LOC607405 Protein, CLEC10A Protein, Clec10a Protein
- Background
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Description: CLEC10A, also known as macrophage galactose/N-acetyl-galactosamine (GalNAc) specific lectin (MGL), CD301, DC-ASGPR, and HML, is a 40 kDa type II transmembrane glycoprotein that belongs to the C-type lectin family. C-type lectin family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. CLEC10A is expressed on macrophages and related cells of myeloid origins, particularly immature dendritic cells (DCs). CLEC10A plays a protective role against colitis by effectively inducing IL-10 production by colonic lamina propria macrophages in response to invading commensal bacteria.
Name: CLEC10A,CD301,CLECSF13,CLECSF14,HML,HML2,MGL
- Gene ID
- 10462
- UniProt
- Q8IUN9
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