CHST11 Protein (His tag)

Catalog No. ABIN7317567

Product Details

Target: CHST11 (Carbohydrate (Chondroitin 4) Sulfotransferase 11 (CHST11))

Protein Type: Recombinant

Origin: Human

Source: Baculovirus infected Insect Cells

Purification tag / Conjugate: This CHST11 protein is labelled with His tag.

Purpose: Recombinant Human CHST11/C4ST-1 Protein (His Tag)

Sequence: Met36-Glu347

Characteristics: A DNA sequence encoding the human CHST11 (Q9NPF2-2) (Met36-Glu347) was expressed with a C-terminal polyhistidine tag.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 10 % glycerol, pH 7.4

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: CHST11 (Carbohydrate (Chondroitin 4) Sulfotransferase 11 (CHST11))

Alternative Name: CHST11/C4ST-1 (CHST11 Products)

Synonyms: C4ST Protein, C4ST-1 Protein, C4ST1 Protein, HSA269537 Protein, 1110020P09Rik Protein, C4s Protein, carbohydrate sulfotransferase 11 Protein, carbohydrate (chondroitin 4) sulfotransferase 11 Protein, CHST11 Protein, Chst11 Protein, chst11 Protein

Background:

Background: CHST11, also known as C4ST-1, belongs to the sulfotransferase 2 family. CHST11 localizes to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage, and is distributed on the surfaces of many cells and extracellular matrices. A chromosomal translocation involving CHST11 gene and IgH, t(12,14)(q23,q32), has been reported in a patient with B-cell chronic lymphocytic leukemia.

Synonym: C4ST,C4ST-1,C4ST1,HSA269537

Molecular Weight: 38.4 kDa

Pathways: Glycosaminoglycan Metabolic Process