Carbonic Anhydrase 14 (CAR14) (Active) protein (His tag)
-
- Target
- Carbonic Anhydrase 14 (CAR14)
- Protein Type
- Recombinant
- Biological Activity
- Active
- Origin
- Mouse
-
Source
- Human Cells
- Purification tag / Conjugate
- His tag
- Purpose
- Recombinant Mouse Carbonic Anhydrase 14/Car14 Protein (His Tag)(Active)
- Sequence
- Ala16-Met290
- Characteristics
- Recombinant Mouse Carbonic anhydrase 14 is produced by our Mammalian expression system and the target gene encoding Ala16-Met290 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by SDS-PAGE
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Measured by its esterase activity. The specific activity is 6556.875 pmol/min/ug, as measured under the described conditions.
-
Carbonic Anhydrase 14 (CAR14) protein (His tag)
CAR14 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE
-
- Restrictions
- For Research Use only
-
- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM Tris,150 mM NaCl, pH 8.0.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
-
- Target
- Carbonic Anhydrase 14 (CAR14)
- Alternative Name
- Carbonic Anhydrase 14/Car14
- Synonyms
- AW536446 Protein, Ca14 Protein, carbonic anhydrase 14 Protein, Car14 Protein
- Background
-
Background: Mouse Ca14,also known as Carbonic anhydrase 14,is a member of large family of zinc metalloenzymes .It could catalyze reversible hydration of carbon dioxide. The reaction is fundamental to many processes such as respiration, renal tubular acidification and bone resorption. Fifteen CA isoforms have been reported so far. They have different patterns of tissue-specific expression and physiologic roles. Some CAs may serve as markers for tumors and hypoxia. CA XIV is a polypeptide consisting of an extracellular N-terminal catalytic domain, a membrane-spanning segment and a short intracellular C- terminal segment with several potential phosphorylation sites. A subset of CAs lack CA activity due to point mutations but retain esterase function. CA14 is widely expressed in the central nervous system
Synonym: Carbonic Anhydrase 14, Carbonate Dehydratase XIV, Carbonic Anhydrase XIV, CA-XIV, CA14,
- Molecular Weight
- 31.8 kDa
- UniProt
- Q9WVT6
-
