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CA4 Protein (AA 18-277) (His tag)

CA4 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Catalog No. ABIN7320479
  • Target See all CA4 Proteins
    CA4 (Carbonic Anhydrase IV (CA4))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 18-277
    Origin
    • 8
    • 5
    • 3
    • 1
    • 1
    Mouse
    Source
    • 7
    • 3
    • 3
    • 2
    • 2
    • 1
    Human Cells
    Purification tag / Conjugate
    This CA4 protein is labelled with His tag.
    Purpose
    Recombinant Mouse Carbonic Anhydrase 4/CA4 Protein (aa 18-277, His Tag)
    Sequence
    Glu18-Ser277
    Characteristics
    Recombinant Mouse Carbonic anhydrase 4 is produced by our Mammalian expression system and the target gene encoding Glu18-Ser277 is expressed with a 6His tag at the C-terminus.
    Purity
    > 95 % as determined by SDS-PAGE
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CA4 Protein
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM Tris,150 mM NaCl, pH 8.0.
    Storage
    -20 °C
    Storage Comment
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    CA4 (Carbonic Anhydrase IV (CA4))
    Alternative Name
    Carbonic Anhydrase 4/CA4 (CA4 Products)
    Synonyms
    CAIV Protein, Car4 Protein, RP17 Protein, AW456718 Protein, Ca4 Protein, ca4 Protein, caiv Protein, car4 Protein, rp17 Protein, CA4 Protein, zgc:171842 Protein, carbonic anhydrase 4 Protein, carbonic anhydrase 4 S homeolog Protein, carbonic anhydrase IV a Protein, CA4 Protein, Car4 Protein, ca4 Protein, ca4.S Protein, Ca4 Protein, ca4a Protein
    Background

    Background: Carbonic anhydrase 4(CA4) is an enzyme that belongs to the alpha-carbonic anhydrase family. CA4 consists of a signal peptide (residues1-17), an ectodomain (residues18-277) and a propeptide (residues278-305), which is removed in the mature form. it is predominantly expressed in the embryo. CA4 can catalyzes the reversible reaction of CO2+H2O=HCO3-+H+, and stimulates the sodium/bicarbonate transporter activity of SLC4A4. Studies have shown that this protein have a role in inherited renal abnormalities of bicarbonate transport. Alpha-carbonic anhydrase family participate in avariety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor. They show extensive diversity in tissue is attribution and in their sub cellular localization.

    Synonym: CA4,CAIV,CA-IV,Car4,Carbonate dehydratase IV,carbonic anhydrase 4,carbonic anhydrase IVRP17,carbonic dehydratase IV,EC4.2.1.1,retinitis pigmentosa 17,RP17

    Molecular Weight
    30.5 kDa
    UniProt
    Q64444
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