CER1 Protein (His tag)
-
- Target See all CER1 Proteins
- CER1 (Cerberus 1 Homolog (Xenopus Laevis) (CER1))
- Protein Type
- Recombinant
-
Origin
- Human
-
Source
- Human Cells
- Purification tag / Conjugate
- This CER1 protein is labelled with His tag.
- Purpose
- Recombinant Human Cerberus/CER1 Protein (His Tag)
- Sequence
- Thr18-Ala267
- Characteristics
- Recombinant Human Cerberus 1 is produced by our Mammalian expression system and the target gene encoding Thr18-Ala267 is expressed with a 6His tag at the C-terminus.
- Purity
- > 90 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CER1 Protein
-
Cerberus 1 Homolog (Xenopus Laevis) (CER1) (AA 1-267) protein (GST tag)
CER1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Cerberus 1 Homolog (Xenopus Laevis) (CER1) (AA 158-266) protein (GST tag)CER1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Cerberus 1 Homolog (Xenopus Laevis) (CER1) (AA 18-267) protein (His tag)Crystallography grade CER1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Cerberus 1 Homolog (Xenopus Laevis) (CER1) (AA 18-272) protein (His tag)Crystallography grade CER1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM HAc.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
- Target
- CER1 (Cerberus 1 Homolog (Xenopus Laevis) (CER1))
- Alternative Name
- Cerberus/CER1 (CER1 Products)
- Synonyms
- DAND4 Protein, CAR Protein, cer Protein, cer-1 Protein, dand4 Protein, tCerberus Protein, xcer-1 Protein, xcer1 Protein, Cerl Protein, Cerl1 Protein, Cerr1 Protein, RGD1563046 Protein, cerberus 1, DAN family BMP antagonist Protein, cerberus 1, DAN family BMP antagonist S homeolog Protein, CER1 Protein, cer1.S Protein, Cer1 Protein
- Background
-
Background: Cerberus 1 is a secreted glycoprotein that forms disulfide-linked homodimers. It is a cytokine member of the DAN domain family of BMP antagonists that includes DAN (DAND1), Gremlin/Drm (DAND2), PRDC (Protein Related to Dan and Cerberus, DAND3), and COCO/Dante (DAND5). DAN family members contain a cysteine knot domain that is homologous to that found in other TGF-beta superfamily ligands. At the onset of gastrulation, Cerberus 1 is transiently expressed in anterior endodermal structures in response to Nodal and Shh. Cerberus 1 binds BMP-4 and Nodal and inhibits their activities. The inhibitory functions of Cerberus favor mesodermal development in the anterior region of the gastrula and suppresses posterior mesodermal differentiation. In chick and Xenopus, Cerberus 1 also regulates, but is not required for embryonic left-right polarization, neurulation, and head and heart induction.
Synonym: Cerberus, Cerberus-Related Protein, DAN Domain Family Member 4, CER1, DAND4
- Molecular Weight
- 29.2 kDa
- UniProt
- O95813
- Pathways
- Maintenance of Protein Location
-
