Contactin 5 Protein (CNTN5) (His tag)
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- Target See all Contactin 5 (CNTN5) Proteins
- Contactin 5 (CNTN5)
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Contactin 5 protein is labelled with His tag.
- Purpose
- Recombinant Mouse Contactin 5/CNTN5 Protein (His Tag)(Active)
- Sequence
- Met1-Gln1058
- Characteristics
- A DNA sequence encoding the mouse CNTN5 (P68500) (Met1-Gln1058) was expressed with a C-terminal polyhistidine tag.
- Purity
- > 85 % as determined by SDS-PAGE
- Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Biological Activity Comment
- Measured by the ability of the immobilized protein to support the adhesion of C6 cells.When 5 x 10E4 cells/well are added to CNTN5-coated plates (0.8 μg/mL and 100 μL/well), approximately >70% cells will adhere specifically after 60 minutes at 37°C.
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Contactin 5 (CNTN5) (AA 19-1072) protein (His tag)
Crystallography grade CNTN5 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Contactin 5 (CNTN5) (AA 24-1071) protein (His tag)Crystallography grade CNTN5 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- Contactin 5 (CNTN5)
- Alternative Name
- Contactin 5/CNTN5 (CNTN5 Products)
- Synonyms
- MGC151600 Protein, HNB-2s Protein, NB-2 Protein, 6720426O10Rik Protein, A830025P08Rik Protein, Gm507 Protein, Nb-2 Protein, FAR-2 Protein, fi09g01 Protein, wu:fi09g01 Protein, zgc:55318 Protein, contactin 5 Protein, contactin-5 Protein, CNTN5 Protein, cntn5 Protein, Tsp_09341 Protein, Cntn5 Protein
- Background
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Background: Contactins are a subgroup of molecules belonging to the immunoglobulin superfamily that are expressed mainly in the nervous system. The subgroup consists of six members: Contactin-1, Contactin-2(TAG-1), Contactin-3(BIG-1), BIG-2, Contactin-5(NB-2) and NB-3. Since their identification in the late 1980s, Contactin-1 and Contactin-2 have been studied extensively. Axonal expression and the neurite extension activity of Contactin-1 and Contactin-2 attracted researchers to study the function of these molecules in axon guidance during development. Contactin-1 and Contactin-2 have come to be known as the principal molecules in the function and maintenance of myelinated neurons. In contrast, the function of the other four members of this subgroup remained unknown until recently. Contactin-5, also known as NB-2, is one of the neural recognition molecules in the contactin subgroup. Contactin-5 is expressed in brain and kidney and at very low level in placenta. In brain, Contactin-5 is highly expressed in the occipital lobe, amygdala, cerebral cortex, frontal lobe, thalamus and temporal lobe. Mice deficient in the Contactin-5 gene exhibit aberrant responses to acoustic stimuli. Contactin-5 may play a role in maturation of glutamatergic synapses in the brainstem during the final stages of auditory development. Contactin-5 gene may contribute to human neurological disorders.
Synonym: 6720426O10Rik,A830025P08Rik,Gm507,NB-2
- Molecular Weight
- 115.2 kDa
- UniProt
- P68500
- Pathways
- Sensory Perception of Sound
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