CDKN2C Protein (His tag)
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- Target See all CDKN2C Proteins
- CDKN2C (Cyclin-Dependent Kinase Inhibitor 2C (p18, Inhibits CDK4) (CDKN2C))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CDKN2C protein is labelled with His tag.
- Purpose
- Recombinant Human CDKN2C Protein (His Tag)
- Sequence
- Met 1-Gln168
- Characteristics
- Recombinant Human Cyclin-Dependent Kinase 4 Inhibitor C is produced by our E.coli expression system and the target gene encoding Met1-Gln168 is expressed with a 6His tag at the N-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CDKN2C Protein
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Cyclin-Dependent Kinase Inhibitor 2C (p18, Inhibits CDK4) (CDKN2C) (AA 1-168) protein (His tag)
CDKN2C Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Cyclin-Dependent Kinase Inhibitor 2C (p18, Inhibits CDK4) (CDKN2C) (AA 1-168) protein (GST tag)CDKN2C Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Cyclin-Dependent Kinase Inhibitor 2C (p18, Inhibits CDK4) (CDKN2C) (AA 1-168) protein (Strep Tag)Crystallography grade CDKN2C Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Cyclin-Dependent Kinase Inhibitor 2C (p18, Inhibits CDK4) (CDKN2C) (Transcript Variant 1) protein (His tag)CDKN2C Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Cyclin-Dependent Kinase Inhibitor 2C (p18, Inhibits CDK4) (CDKN2C) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)CDKN2C Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Cyclin-Dependent Kinase Inhibitor 2C (p18, Inhibits CDK4) (CDKN2C) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)CDKN2C Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 8.0.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- CDKN2C (Cyclin-Dependent Kinase Inhibitor 2C (p18, Inhibits CDK4) (CDKN2C))
- Alternative Name
- CDKN2C (CDKN2C Products)
- Synonyms
- CDKN2C Protein, p18 Protein, ink4c Protein, p18-ink4c Protein, INK4C Protein, p18-INK4C Protein, C77269 Protein, INK4c Protein, INK4d Protein, p18INK4c Protein, cyclin dependent kinase inhibitor 2C Protein, cyclin-dependent kinase inhibitor 2C Protein, cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) Protein, CDKN2C Protein, cdkn2c Protein, Cdkn2c Protein
- Background
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Background: Cyclin-Dependent Kinase 4 Inhibitor C (CDKN2C) is a member of the INK4 family of cyclin dependent kinase inhibitors. CDKN2C contains 4 ANK repeats and interacts with CDK4 or CDK6. Highest levels of CDKN2C can be found in skeletal muscle, pancreas, and heart. CDKN2C inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB and prevent the activation of the CDK kinases. Studies have been shown the roles of CDKN2C gene in regulating spermatogenesis, as well as in suppressing tumorigenesis.
Synonym: Cyclin-Dependent Kinase 4 Inhibitor C, Cyclin-Dependent Kinase 6 Inhibitor, p18-INK4c, p18-INK6, CDKN2C, CDKN6
- Molecular Weight
- 20.3 kDa
- UniProt
- P42773
- Pathways
- Cell Division Cycle, Mitotic G1-G1/S Phases
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