CRISP3 Protein (His tag)

Catalog No. ABIN7318382

This Recombinant CRISP3 protein is expressed in Human Cells.

Quick Overview for CRISP3 Protein (His tag) (ABIN7318382)

Target: CRISP3 (Cysteine-Rich Secretory Protein 3 (CRISP3))

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purity: > 90 % as determined by reducing SDS-PAGE.

Product Details

Purification tag / Conjugate: This CRISP3 protein is labelled with His tag.

Purpose: Recombinant Human CRISP3/SGP28 Protein (His Tag)

Sequence: Asn21-Tyr245

Characteristics: Recombinant Human Cysteine-Rich Secretory Protein 3 is produced by our Mammalian expression system and the target gene encoding Asn21-Tyr245 is expressed with a 6His tag at the C-terminus.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: CRISP3 (Cysteine-Rich Secretory Protein 3 (CRISP3))

Alternative Name: CRISP3/SGP28

Background:

Background: Cysteine-rich secretory protein 3 (CRISP-3) is a secreted protein,containing 1 SCP domain and 1 ShKT domain.It is belongs to the CRISP family. CRISP-3 is a glycoprotein that belongs to the family of cysteine-rich secretory proteins (CRISPs) which was originally discovered in human neutrophilic granulocytes. CRISP-3 is also widely distibuted in exocrine glands (salivary glands, pancreas and prostate), eosinophilic granulocytes and to a lower level in epididymis, ovary, thymus and colon. The presence of CRISP-3 in neutrophils, eosinophils and in exocrine secretions indicates a role in innate host defense. The antibody has been raised against recombinant C-terminally truncated form of CRISP-3 and recognizes both the N-glycosylated and non-glycosylated form of the mature protein.

Synonym: Cysteine-Rich Secretory Protein 3, CRISP-3, Specific Granule Protein of 28 kDa, SGP28, CRISP3

Molecular Weight: 26.5 kDa

UniProt: P54108