DCBLD2 Protein (AA 1-482) (His tag)

Catalog No. ABIN7317223

Product Details

Target: DCBLD2 (Discoidin, CUB and LCCL Domain Containing 2 (DCBLD2))

Protein Type: Recombinant

Protein Characteristics: AA 1-482

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This DCBLD2 protein is labelled with His tag.

Purpose: Recombinant Human DCBLD2/ESDN Protein (aa 1-482, His Tag)

Sequence: Met 1-Ala482

Characteristics: A DNA sequence encoding the human DCBLD2 (NP_563615.3) (Met1-Ala482) was expressed with a polyhistidine tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: DCBLD2 (Discoidin, CUB and LCCL Domain Containing 2 (DCBLD2))

Alternative Name: DCBLD2/ESDN (DCBLD2 Products)

Synonyms: DCBLD2 Protein, zgc:158743 Protein, CLCP1 Protein, ESDN Protein, 1700055P21Rik Protein, AW146002 Protein, Esdn Protein, discoidin, CUB and LCCL domain containing 2 Protein, discoidin, CUB and LCCL domain-containing protein 2 Protein, DCBLD2 Protein, dcbld2 Protein, LOC100444682 Protein, Dcbld2 Protein

Background:

Background: DCBLD2, also known as ESDN and CLCP1, localizes in various compartments. DCBLD2 is up-regulated in lung cancers and is regulated by transcription factor AP-2 alpha (TFAP2A), a component of activator protein-2 (AP-2) that is known to regulate IL-8 production in human lung fibroblasts and epithelial cells. DCBLD2 could be related to FEV(1)-related phenotypes in asthmatics. DCBLD2 gene is expressed at very high level. DCBLD2 is proposed to participate in processes such as intracellular receptor mediated signaling pathway, negative regulation of cell growth and so on.

Synonym: Discoidin, CUB and LCCL domain-containing protein 2,DCBLD2,CUB, LCCL and coagulation factor V/VIII-homology domains protein 1,Endothelial and smooth muscle cell-derived neuropilin-like protein,DCBLD2,CLCP1, ESDN

Molecular Weight: 52.6 kDa

NCBI Accession: NP_563615