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EDIL3 Protein (His tag)

DEL1 Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7318421
  • Target See all EDIL3 (DEL1) Proteins
    EDIL3 (DEL1) (EGF like repeats and discoidin domains 3 (DEL1))
    Protein Type
    Recombinant
    Origin
    • 8
    • 2
    • 1
    • 1
    • 1
    Human
    Source
    • 2
    • 2
    • 2
    • 2
    • 1
    Human Cells
    Purification tag / Conjugate
    This EDIL3 protein is labelled with His tag.
    Purpose
    Recombinant Human EDIL3/Del-1 Protein (His Tag)
    Sequence
    Val17-Glu480
    Characteristics
    Recombinant Human EGF-Like Repeat and Discoidin I-Like Domain-Containing Protein 3 is produced by our Mammalian expression system and the target gene encoding Val17-Glu480 is expressed with a 6His tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product DEL1 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    EDIL3 (DEL1) (EGF like repeats and discoidin domains 3 (DEL1))
    Alternative Name
    EDIL3/Del-1 (DEL1 Products)
    Synonyms
    si:dkey-84i7.1 Protein, Del1 Protein, XDel1 Protein, DEL1 Protein, Del-1 Protein, EGF-like repeats and discoidin I-like domains 3a Protein, EGF like repeats and discoidin domains 3 L homeolog Protein, EGF like repeats and discoidin domains 3 Protein, EGF-like repeats and discoidin I-like domains 3 Protein, edil3a Protein, edil3.L Protein, EDIL3 Protein, Edil3 Protein
    Background

    Background: EGF-Like Repeat and Discoidin I-Like Domain-Containing Protein 3 (EDIL3) is a 52 kDa extracellular matrix protein that is expressed by endothelial tissues during embryonic vascular development. EDIL3 becomes quiescent at the time of birth, and is no longer expressed in normal adult tissues. EDIL3 has been found to be re-expressed in a number of human tumors as well as in ischemic muscles and ischemic brain tissue, which may play an important role in adult angiogenesis. EDIL3 promotes adherence and migration of endothelial cells, and acts as an endothelial cell survival agent through upregulation of Bcl-2 expression. EDIL3 has also been shown to be an endogenous inhibitor of inflammatory cell recruitment by interfering with the integrin LFA-1-dependent leukocyte-endothelial adhesion. Human EDIL3 is synthesized as a precursor with a 16 amino acid signal sequence and a 464 amino acid mature chain.

    Synonym: EGF-Like Repeats and Discoidin I-Like Domains 3, EDIL3

    Molecular Weight
    53.1 kDa
    UniProt
    Q8N610
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