EDNRB Protein (Fc Tag)
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- Target See all EDNRB Proteins
- EDNRB (Endothelin Receptor Type B (EDNRB))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This EDNRB protein is labelled with Fc Tag.
- Purpose
- Recombinant Human EDNRB/Endothelin B Receptor Protein (Fc Tag)
- Sequence
- Met 1-Lys101
- Characteristics
- A DNA sequence encoding the human EDNRB (NP_000106.1) (Met1-Lys101) was expressed with the Fc region of mouse IgG1 at the C-terminus.
- Purity
- > 85 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Top Product
- Discover our top product EDNRB Protein
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Endothelin Receptor Type B (EDNRB) (AA 27-101) protein (GST tag)
EDNRB Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Endothelin Receptor Type B (EDNRB) (AA 1-442) protein (GST tag)EDNRB Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Endothelin Receptor Type B (EDNRB) (AA 27-442) protein (rho-1D4 tag)Crystallography grade EDNRB Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Endothelin Receptor Type B (EDNRB) (AA 27-442) protein (rho-1D4 tag)Crystallography grade EDNRB Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Endothelin Receptor Type B (EDNRB) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)EDNRB Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- EDNRB (Endothelin Receptor Type B (EDNRB))
- Alternative Name
- EDNRB/Endothelin B Receptor (EDNRB Products)
- Synonyms
- ABCDS Protein, ET-B Protein, ET-BR Protein, ETB Protein, ETBR Protein, ETRB Protein, HSCR Protein, HSCR2 Protein, WS4A Protein, Ednra Protein, Etb Protein, ETR-b Protein, ETb Protein, Sox10m1 Protein, EDNRB Protein, abcds Protein, etb Protein, etrb Protein, hscr Protein, hscr2 Protein, endothelin receptor type B Protein, EDNRB Protein, Ednrb Protein, ednrb Protein
- Background
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Background: The hypermethylation of EDNRB gene was remarkably related to infiltration and metastasis of gastric cancer and may attribute to the tumor progression. EDNRB is a new candidate tumor suppressor gene which is often down-regulated or even silenced by promoter hypermethylation in various human cancers. Low EDNRB expression played a role in the progression of ACC tumors. The autosomal recessive mutation in EDNRB may underlie a part of WS1 with the current diagnostic criteria, and supported that Hirschsprung's disease is a multifactorial genetic disease which requires additional factors.
Synonym: ABCDS,ET-B,ET-BR,ETB,ETBR,ETRB,HSCR,HSCR2,WS4A
- Molecular Weight
- 34.4 kDa
- NCBI Accession
- NP_000106
- Pathways
- Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process
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