EIF2C3 Protein (His tag)
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- Target See all EIF2C3 Proteins
- EIF2C3 (Eukaryotic Translation Initiation Factor 2C3 (EIF2C3))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This EIF2C3 protein is labelled with His tag.
- Purpose
- Recombinant Human AGO3/Argonaute 3/EIF2C3 Protein (His Tag)
- Sequence
- Met 1-Ala 860
- Characteristics
- A DNA sequence encoding the human EIF2C3 (Q9H9G7-1) (Met 1-Ala 860) was expressed, with a polyhistidine tag at the N-terminus.
- Purity
- > 88 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Top Product
- Discover our top product EIF2C3 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 7.4, 10 % glycerol
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- EIF2C3 (Eukaryotic Translation Initiation Factor 2C3 (EIF2C3))
- Alternative Name
- AGO3/Argonaute 3/EIF2C3 (EIF2C3 Products)
- Synonyms
- EIF2C3 Protein, Eif2c3 Protein, Argonaute3 Protein, ago3 Protein, eif2c3 Protein, eif2c3b Protein, si:dkey-3n22.3 Protein, AW048688 Protein, C130014L07Rik Protein, ARGONAUTE 3 Protein, T19E23.8 Protein, T19E23_8 Protein, argonaute 3, RISC catalytic component Protein, argonaute RISC catalytic component 3b Protein, argonaute RISC catalytic subunit 3 Protein, argonaute RISC catalytic component 3 Protein, ARGONAUTE 3 Protein, AGO3 Protein, Ago3 Protein, ago3b Protein
- Background
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Background: Hydroxysteroid sulfotransferase ( SULT2A1 ) is a key enzyme in the testicular and hepatic metabolism of 5alpha-androstenone, which is a major component of the off-odor and off-flavor in pork known as boar taint. Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. SULT2A1 is a sulfo-conjugating phase II enzyme expressed at very high levels in the liver and intestine, the two major first-pass metabolic tissues, and in the steroidogenic adrenal tissue. SULT2A1 acts preferentially on the hydroxysteroids dehydroepiandrosterone, testosterone/dihydrotestosterone, and pregnenolone and on cholesterol-derived amphipathic sterol bile acids.
Synonym: EIF2C3
- Molecular Weight
- 99.6 kDa
- Pathways
- Fc-epsilon Receptor Signaling Pathway, Regulatory RNA Pathways, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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