FCGR1A Protein (His tag)
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- Target See all FCGR1A Proteins
- FCGR1A (Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This FCGR1A protein is labelled with His tag.
- Purpose
- Recombinant Human FCGR1A/CD64 Protein (His Tag)(Active)
- Sequence
- Gln16-Pro288
- Characteristics
- Recombinant Human FCGR1A is produced by our Mammalian expression system and the target gene encoding Gln16-Pro288 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Immobilized Human SIgG1-Fc(Cat: PKSH032558) at 2μg/ml(100 μl/well) can bind Human CD64-His(Cat: PKSM041277). The ED50 of Human CD64-His is 0.05ug/ml .
- Top Product
- Discover our top product FCGR1A Protein
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Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A) (AA 16-115) protein (GST tag)
FCGR1A Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A) (AA 25-297) (Active) protein (His tag)FCGR1A Origin: Mouse Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A) (AA 11-288) (Active) protein (His tag,AVI tag,Biotin)FCGR1A Origin: Cynomolgus Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A) (AA 1-374) protein (GST tag)FCGR1A Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A) (Active) protein (His tag)FCGR1A Origin: Rat Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A) (AA 16-292) protein (His tag)Crystallography grade FCGR1A Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A) (AA 16-374) protein (rho-1D4 tag)Crystallography grade FCGR1A Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A) (AA 16-281) (Active) protein (His tag)FCGR1A Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A) (AA 16-288) (Active) protein (His tag,AVI tag,Biotin)FCGR1A Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by reduced SDS-PAGE. Active
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- FCGR1A (Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A))
- Alternative Name
- FCGR1A/CD64 (FCGR1A Products)
- Synonyms
- CD64 Protein, CD64A Protein, FCRI Protein, IGFR1 Protein, FcgammaRI Protein, Fcgr1 Protein, Fcgr1b Protein, AI323638 Protein, AV092959 Protein, IGGHAFC Protein, FCGR1A Protein, Fc fragment of IgG receptor Ia Protein, Fc receptor, IgG, high affinity I Protein, FCGR1A Protein, Fcgr1a Protein, Fcgr1 Protein
- Background
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Background: CD64 (FcγRI), one of the Fc receptors for IgG, is a membrane glycoprotein that mediates endocytosis, phagocytosis, antibody-dependent cellular cytotoxicity, cytokine release, and superoxide production. CD64 is also structurally distinct, containing an extracellular Ig-interactive region of three Ig-like domains in contrast to the two domains of the low affinity receptors FcγRII and FcγRIII. It is normally expressed on the surfaces of monocytes and macrophages.
Synonym: Ig gamma-4 chain C region,IgG4 Fc
- Molecular Weight
- 31.7 kDa
- UniProt
- P12314
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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