FCRL1 Protein (His tag)

Catalog No. ABIN7319315

Product Details

Target: FCRL1 (Fc Receptor-Like 1 (FCRL1))

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This FCRL1 protein is labelled with His tag.

Purpose: Recombinant Human FCRL1 Protein (His Tag)

Sequence: Ala17-Asn303

Characteristics: Recombinant Human Fc Receptor-Like Protein 1 is produced by our Mammalian expression system and the target gene encoding Ala17-Asn303 is expressed with a 6His tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 1 mM EDTA, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: FCRL1 (Fc Receptor-Like 1 (FCRL1))

Alternative Name: FCRL1 (FCRL1 Products)

Synonyms: CD307a Protein, FCRH1 Protein, IFGP1 Protein, IRTA5 Protein, A230020G22Rik Protein, Bxmas1 Protein, Bxmh1 Protein, Bxmh1b Protein, Fcrh1 Protein, Fcrh1l Protein, Fcrh1s Protein, Ifgp1 Protein, FCRL1 Protein, MGC148384 Protein, Fc receptor like 1 Protein, Fc receptor-like 1 Protein, Fc receptor-like protein 1 Protein, FCRL1 Protein, Fcrl1 Protein, LOC612035 Protein

Background:

Background: Fc Receptor-Like Protein 1 (FCRL1) is a single-pass type I membrane protein that may function as an activating coreceptor in B cells. FCRL1 is primarily expressed in secondary lymphoid tissues by mature subsets of B cells. It can be detected in the spleen, lymph node, heart, skeletal muscle, kidney, liver and placenta. It is specifically expressed by mature B lineage cells with higher expression at the protein level in naive B cells compared to memory B cells. FCRL1 contains three extracellular C2-like immunoglobulin domains, a transmembrane domain, and a cytoplasmic domain with two immunoreceptor-tyrosine activation motifs and may play a role in the regulation of cancer cell growth.

Synonym: Fc Receptor-Like Protein 1, FcR-Like Protein 1, FcRL1, Fc Receptor Homolog 1, FcRH1, IFGP Family Protein 1, hIFGP1, Immune Receptor Translocation-Associated Protein 5, CD307a, FCRL1, FCRH1, IFGP1, IRTA5

Molecular Weight: 32.2 kDa

UniProt: Q96LA6