FCRL1 Protein (AA 1-204) (His tag)

Catalog No. ABIN7320103

Product Details

Target: FCRL1 (Fc Receptor-Like 1 (FCRL1))

Protein Type: Recombinant

Protein Characteristics: AA 1-204

Origin: Mouse

Source: HEK-293 Cells

Purification tag / Conjugate: This FCRL1 protein is labelled with His tag.

Purpose: Recombinant Mouse FCRL1 Protein (aa 1-204, His Tag)

Sequence: Met1-Thr204

Characteristics: A DNA sequence encoding the mouse FCRL1 (Q8R4Y0-2) (Met1-Thr204) was expressed with a C-terminal polyhistidine tag.

Purity: > 95 % as determined by SDS-PAGE

Endotoxin Level: < 1.0 EU per μg of the protein as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: FCRL1 (Fc Receptor-Like 1 (FCRL1))

Alternative Name: FCRL1 (FCRL1 Products)

Synonyms: CD307a Protein, FCRH1 Protein, IFGP1 Protein, IRTA5 Protein, A230020G22Rik Protein, Bxmas1 Protein, Bxmh1 Protein, Bxmh1b Protein, Fcrh1 Protein, Fcrh1l Protein, Fcrh1s Protein, Ifgp1 Protein, FCRL1 Protein, MGC148384 Protein, Fc receptor like 1 Protein, Fc receptor-like 1 Protein, Fc receptor-like protein 1 Protein, FCRL1 Protein, Fcrl1 Protein, LOC612035 Protein

Background:

Background: Fc receptor-like protein 1, also known as FcR-like protein 1, Fc receptor homolog 1, IFGP family protein 1, Immune receptor translocation-associated protein 5 and FCRL1, is a single-pass type I  membrane protein which contains three Ig-like C2-type (immunoglobulin-like) domains. It is a cell-surface membrane protein belonging to FCRL family and is preferentially expressed on B cells. FCRL1 is primarily expressed in secondary lymphoid tissues by mature subsets of B cells. It is detected in spleen, lymph node, heart, skeletal muscle, kidney, liver and placenta. FCRL1 is specifically expressed by mature B lineage cells with higher expression in naive versus memory B cells (at protein level). Human Fc receptor-like molecules (FCRL1, FCRL2, FCRL3, FCRL4, FCRL5) have tyrosine-based immunoregulatory potential and are expressed by B-lineage subpopulations. FCRL1 may function as an activating coreceptor in B cells. It may also function in B cells activation and differentiation.

Synonym: Fc receptor-like protein 1; FcR-like protein 1; FcRL1; BXMAS1-like protein 1; mBXMH1; Fc receptor homolog 1; FcRH1; moFcRH1; IFGP family protein 1; mIFGP1; CD307a;Bxmas1;Bxmh1;Bxmh1b;Fcrh1;Fcrh1l;Fcrh1s;Ifgp1 Protein

Molecular Weight: 21.6 kDa