FZD6 Protein (Fc Tag)
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- Target See all FZD6 Proteins
- FZD6 (Frizzled Family Receptor 6 (FZD6))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This FZD6 protein is labelled with Fc Tag.
- Purpose
- Recombinant Human Frizzled-6/FZD6 Protein (Fc Tag)
- Sequence
- Met 1-Val153
- Characteristics
- A DNA sequence encoding the human FZD6 (NP_003497.2) (Met1-Val153) was expressed with the Fc region of mouse IgG1 at the C-terminus.
- Purity
- > 90 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Top Product
- Discover our top product FZD6 Protein
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Frizzled Family Receptor 6 (FZD6) (AA 71-181) protein (GST tag)
FZD6 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- FZD6 (Frizzled Family Receptor 6 (FZD6))
- Alternative Name
- Frizzled-6/FZD6 (FZD6 Products)
- Synonyms
- zgc:65879 Protein, zgc:77440 Protein, fz6 Protein, frz6 Protein, Xfrz6 Protein, frizzled6 Protein, frizzled-6 Protein, FZ-6 Protein, FZ6 Protein, HFZ6 Protein, NDNC10 Protein, Frizzled-6 Protein, Fz6 Protein, frizzled class receptor 6 Protein, frizzled class receptor 6 S homeolog Protein, fzd6 Protein, fzd6.S Protein, FZD6 Protein, Fzd6 Protein
- Background
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Background: This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide.
Synonym: FZ-6,FZ6,HFZ6,NDNC10
- Molecular Weight
- 42 kDa
- NCBI Accession
- NP_003497
- Pathways
- WNT Signaling, Tube Formation
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