GSK3 alpha Protein
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- Target See all GSK3 alpha (GSK3a) Proteins
- GSK3 alpha (GSK3a) (Glycogen Synthase Kinase 3 alpha (GSK3a))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purpose
- Recombinant Human GSK3α Protein
- Sequence
- Ser97-Pro448
- Characteristics
- A DNA sequence encoding the Human GSK3α Protein (P49840)(97-448)was expressed with a polyhistidine tag at the N-terminus.
- Purity
- > 80 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product GSK3a Protein
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Glycogen Synthase Kinase 3 alpha (GSK3a) (AA 393-483) protein (GST tag)
GSK3a Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Glycogen Synthase Kinase 3 alpha (GSK3a) (AA 2-483) protein (His tag)Crystallography grade GSK3a Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Glycogen Synthase Kinase 3 alpha (GSK3a) (AA 2-490) protein (His tag)Crystallography grade GSK3a Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Glycogen Synthase Kinase 3 alpha (GSK3a) protein (Myc-DYKDDDDK Tag)GSK3a Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Glycogen Synthase Kinase 3 alpha (GSK3a) proteinGSK3a Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, ELISA, IP
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.5, 5 % trehalose, 5 % mannitol, 0.01 % tween-80.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- GSK3 alpha (GSK3a) (Glycogen Synthase Kinase 3 alpha (GSK3a))
- Alternative Name
- GSK3alpha (GSK3a Products)
- Synonyms
- 2700086H06Rik Protein, GSK3A Protein, GSK-3[a] Protein, GSK-3[b] Protein, GSK3 Protein, gsk3a Protein, xgsk3 Protein, glycogen synthase kinase 3 alpha Protein, glycogen synthase kinase 3 alpha b Protein, glycogen synthase kinase 3 alpha S homeolog Protein, GSK3A Protein, Gsk3a Protein, gsk3a Protein, gsk3ab Protein, gsk3a.S Protein, Bm1_31380 Protein
- Background
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Background: Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), CTNNB1/beta-catenin, APC and AXIN1.
Synonym: Glycogen synthase kinase-3 alpha,GSK-3 alpha,Serine/threonine-protein kinase GSK3A ,GSK3A
- Molecular Weight
- 39.4 kDa
- NCBI Accession
- NP_063937
- Pathways
- PI3K-Akt Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, cAMP Metabolic Process, Cellular Glucan Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, BCR Signaling, Warburg Effect
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