HK3 Protein (GST tag,His tag)
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- Target See all HK3 Proteins
- HK3 (Hexokinase 3 (White Cell) (HK3))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This HK3 protein is labelled with GST tag,His tag.
- Purpose
- Recombinant Human Hexokinase-3/HK3 Protein (His & GST Tag)
- Sequence
- Met 1-Val 923
- Characteristics
- A DNA sequence encoding the human HK3 (P52790) (Met 1-Val 923) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
- Purity
- > 85 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product HK3 Protein
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as sterile 50 mM Tris, 100 mM NaCl, pH 7.4
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- HK3 (Hexokinase 3 (White Cell) (HK3))
- Alternative Name
- Hexokinase-3/HK3 (HK3 Products)
- Synonyms
- HKIII Protein, HXK3 Protein, APS Protein, KLK2A1 Protein, PSA Protein, hK3 Protein, HK III Protein, HK-III Protein, T2E6.5 Protein, T2E6_5 Protein, hexokinase 3 Protein, RNU73859 Protein, hexokinase 3 Protein, kallikrein related peptidase 3 Protein, HK3 Protein, KLK3 Protein, Hk3 Protein, HXK3 Protein
- Background
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Background: Hexokinase-3, also known as Hexokinase type III, HKIII and HK3, is a protein which belongs to the hexokinase family. Hexokinase-3 / HK3 is an enzyme which in humans is encoded by the HK2 gene. Hexokinases phosphorylate glucose to produce glucose 6-phosphate, committing glucose to the glycolytic pathway. In mammalian tissues hexokinase exists as four isoenzymes encoded by distinct genes. These proteins are homologous and are organized in two homologous domains, with the exception of hexokinase type IV which has only one. This organization is believed to be the result of a duplication and tandem fusion event involving the gene encoding for the ancestral hexokinase. The gene encodes hexokinase-3. Similar to hexokinases-1 and hexokinases-2, this allosteric enzyme is inhibited by its product glucose 6-phosphate.
Synonym: HKIII;HXK3
- Molecular Weight
- 127 kDa
- UniProt
- P52790
- Pathways
- Carbohydrate Homeostasis, Warburg Effect
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