INHBC Protein (AA 19-352) (His tag)
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- Target See all INHBC Proteins
- INHBC (Inhibin, beta C (INHBC))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 19-352
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This INHBC protein is labelled with His tag.
- Purpose
- Recombinant Human Inhibin β C Chain/INHBC Protein (aa 19-352, His Tag)(Active)
- Sequence
- Thr19-Ser352
- Characteristics
- Recombinant Human Inhibin beta C Chain is produced by our Mammalian expression system and the target gene encoding Thr19-Ser352 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Immobilized Human INHBC-His at 0.5μg/ml(100 μl/well) can bind Human ACVR2A-Fc(Cat: PKSH032039). The ED50 of Human INHBC-His is 4.5 ug/ml .
- Top Product
- Discover our top product INHBC Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- INHBC (Inhibin, beta C (INHBC))
- Alternative Name
- Inhibin beta C Chain/INHBC (INHBC Products)
- Synonyms
- IHBC Protein, inhibin beta C subunit Protein, inhibin beta-C Protein, INHBC Protein, Inhbc Protein
- Background
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Background: Inhibin beta C chain, also known as activin beta-C chain and INHBC, belongs to the TGF-beta family. INHBC forms a homodimeric or heterodimeric through association with alpha and beta subunits, linked by one or more disulfide bonds. Inhibins are heterodimers of one alpha and one beta subunit. Activins are homo- or heterodimers of beta subunits only. Inhibins/activins regulates many physiological processes, such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth and so on.
Synonym: Inhibin Beta C Chain, Activin Beta-C Chain, INHBC
- Molecular Weight
- 37.5 kDa
- UniProt
- P55103
- Pathways
- Peptide Hormone Metabolism, Hormone Activity
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