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INHBC Protein (AA 19-352) (His tag)

INHBC Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE. Active
Catalog No. ABIN7318617
  • Target See all INHBC Proteins
    INHBC (Inhibin, beta C (INHBC))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    AA 19-352
    Origin
    • 6
    • 3
    • 3
    Human
    Source
    • 7
    • 2
    • 1
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This INHBC protein is labelled with His tag.
    Purpose
    Recombinant Human Inhibin β C Chain/INHBC Protein (aa 19-352, His Tag)(Active)
    Sequence
    Thr19-Ser352
    Characteristics
    Recombinant Human Inhibin beta C Chain is produced by our Mammalian expression system and the target gene encoding Thr19-Ser352 is expressed with a 6His tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Biological Activity Comment
    Immobilized Human INHBC-His at 0.5μg/ml(100 μl/well) can bind Human ACVR2A-Fc(Cat: PKSH032039). The ED50 of Human INHBC-His is 4.5 ug/ml .
    Top Product
    Discover our top product INHBC Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    INHBC (Inhibin, beta C (INHBC))
    Alternative Name
    Inhibin beta C Chain/INHBC (INHBC Products)
    Synonyms
    IHBC Protein, inhibin beta C subunit Protein, inhibin beta-C Protein, INHBC Protein, Inhbc Protein
    Background

    Background: Inhibin beta C chain, also known as activin beta-C chain and INHBC, belongs to the TGF-beta family. INHBC forms a homodimeric or heterodimeric through association with alpha and beta subunits, linked by one or more disulfide bonds. Inhibins are heterodimers of one alpha and one beta subunit. Activins are homo- or heterodimers of beta subunits only. Inhibins/activins regulates many physiological processes, such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth and so on.

    Synonym: Inhibin Beta C Chain, Activin Beta-C Chain, INHBC

    Molecular Weight
    37.5 kDa
    UniProt
    P55103
    Pathways
    Peptide Hormone Metabolism, Hormone Activity
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