INHBC Protein (AA 237-352) (His tag)
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- Target See all INHBC Proteins
- INHBC (Inhibin, beta C (INHBC))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 237-352
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This INHBC protein is labelled with His tag.
- Purpose
- Recombinant Human Inhibin β C Chain/INHBC Protein (aa 237-352, His Tag)(Active)
- Sequence
- Gly237-Ser352
- Characteristics
- Recombinant Human Inhibin beta C Chain is produced by our E.coli expression system and the target gene encoding Gly237-Ser352 is expressed with a 6His tag at the N-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Immobilized Human INHBC-His at 0.8μg/ml(100 μl/well) can bind Human ACVR2A-Fc(Cat: PKSH032039). The ED50 of Human INHBC-His is 6.73 ug/ml .
- Top Product
- Discover our top product INHBC Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 4 mM HCl, 1 mM DTT.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- INHBC (Inhibin, beta C (INHBC))
- Alternative Name
- Inhibin beta C Chain/INHBC (INHBC Products)
- Synonyms
- IHBC Protein, inhibin beta C subunit Protein, inhibin beta-C Protein, INHBC Protein, Inhbc Protein
- Background
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Background: Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins,Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland.
Synonym: Inhibin Beta C Chain, Activin Beta-C Chain, INHBC
- Molecular Weight
- 14.8 kDa
- UniProt
- P55103
- Pathways
- Peptide Hormone Metabolism, Hormone Activity
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