IL2RG Protein (His tag,Fc Tag)

Catalog No. ABIN7318606

Product Details

Target: IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This IL2RG protein is labelled with His tag,Fc Tag.

Purpose: Recombinant Human IL2RG/CD132 Protein (Fc & His Tag)

Sequence: Leu23-Ala262

Characteristics: Recombinant Human Cytokine receptor common subunit gamma is produced by our Mammalian expression system and the target gene encoding Leu23-Ala262 is expressed with a 6His tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 .

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

Alternative Name: IL2RG/CD132 (IL2RG Products)

Synonyms: Ab2-183 Protein, Cd132 Protein, CD132 Protein, CIDX Protein, IL-2RG Protein, IMD4 Protein, P64 Protein, SCIDX Protein, SCIDX1 Protein, [g]c Protein, gamma(c) Protein, gc Protein, interleukin 2 receptor subunit gamma Protein, interleukin 2 receptor subunit gamma L homeolog Protein, interleukin 2 receptor, gamma chain Protein, IL2RG Protein, il2rg.L Protein, Il2rg Protein

Background:

Background: IL2RG contains one fibronectin type-III domain. IL2RG is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. IL2RG interacts with SHB upon interleukin stimulation and HTLV-1 accessory protein p12I. Defects in IL2RG are the cause of X-linked combined immunodeficiency (XCID) and severe combined immunodeficiency X-linked T-cell-negative /B-cell-positive / NK-cell-negative (XSCID).

Synonym: Cytokine receptor common subunit gamma, Interleukin-2 receptor subunit gamma, gammaC, P64, CD132, IL2RG, SCIDX,SCIDX1, CIDX

Molecular Weight: 29.3 kDa

UniProt: P31785

Pathways: JAK-STAT Signaling, Growth Factor Binding