IPP Isomerase 2 Protein (IDI2) (His tag)
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- Target See all IPP Isomerase 2 (IDI2) Proteins
- IPP Isomerase 2 (IDI2)
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This IPP Isomerase 2 protein is labelled with His tag.
- Purpose
- Recombinant Human IPPI2/IDI2 Protein (His Tag)
- Sequence
- Met 1-Val227
- Characteristics
- Recombinant Human Isopentenyl Pyrophosphate Isomerase 2 is produced by our E.coli expression system and the target gene encoding Met1-Val227 is expressed with a 6His tag at the N-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product IDI2 Protein
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 1 mM DTT, 0.1 mM PMSF, pH 8.0.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- IPP Isomerase 2 (IDI2)
- Alternative Name
- IPPI2/IDI2 (IDI2 Products)
- Synonyms
- 4833405L16Rik Protein, IPPI2 Protein, isopentenyl-diphosphate delta isomerase 2 Protein, Idi2 Protein, IDI2 Protein
- Background
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Background: Isopentenyl Pyrophosphate Isomerase 2 (IDI2) belongs to the IPP isomerase type 1 family. Both isozymes, IDI1 and IDI2 are localized to the peroxisome by a PTS1-dependent pathway. IDI2 is expressed in skeletal muscle, which contains one nudix hydrolase domain. IDI2 binds one magnesium per subunit. IDI2 catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). It is reported that IDI2 is regulated independently from IDI1, by a mechanism that may involve PPAR-α.
Synonym: Isopentenyl-Diphosphate Delta-Isomerase 2, Isopentenyl Pyrophosphate Isomerase 2, IPP Isomerase 2, IPPI2, IDI2
- Molecular Weight
- 28.9 kDa
- UniProt
- Q9BXS1
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