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IPP Isomerase 2 Protein (IDI2) (AA 1-227) (His tag)

IDI2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN1096990
  • Target See all IPP Isomerase 2 (IDI2) Proteins
    IPP Isomerase 2 (IDI2)
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-227
    Origin
    • 4
    • 1
    Human
    Source
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This IPP Isomerase 2 protein is labelled with His tag.
    Purpose
    Recombinant Human Isopentenyl Pyrophosphate Isomerase 2//IPPI2/IDI2 (N-6His)
    Sequence
    MGSSHHHHHH SSGLVPRGSH MSDINLDWVD RRQLQRLEEM LIVVDENDKV IGADTKRNCH LNENIEKGLL HRAFSVVLFN TKNRILIQQR SDTKVTFPGY FTDSCSSHPL YNPAELEEKD AIGVRRAAQR RLQAELGIPG EQISPEDIVF MTIYHHKAKS DRIWGEHEIC YLLLVRKNVT LNPDPSETKS ILYLSQEELW ELLEREARGE VKVTPWLRTI AERFLYRWWP HLDDVTPFVE LHKIHRV
    Characteristics
    Recombinant Human Isopentenyl Pyrophosphate Isomerase 2/IPP Isomerase 2 is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Val227) of Human IDI2 fused with a 6His tag at the N-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Sterility
    0.2 μm filtered
    Endotoxin Level
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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    Discover our top product IDI2 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 1 mM DTT, 0.1 mM PMSF, pH 8.0.
    Preservative
    Dithiothreitol (DTT)
    Precaution of Use
    This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Storage
    -80 °C
    Storage Comment
    Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    IPP Isomerase 2 (IDI2)
    Alternative Name
    IPP-isomerase-2 (IDI2 Products)
    Synonyms
    4833405L16Rik Protein, IPPI2 Protein, isopentenyl-diphosphate delta isomerase 2 Protein, Idi2 Protein, IDI2 Protein
    Sub Type
    Fusionprotein
    Background
    Isopentenyl Pyrophosphate Isomerase 2 (IDI2) belongs to the IPP isomerase type 1 family. Both isozymes, IDI1 and IDI2 are localized to the peroxisome by a PTS1-dependent pathway. IDI2 is expressed in skeletal muscle, which contains one nudix hydrolase domain. IDI2 binds one magnesium per subunit. IDI2 catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). It is reported that IDI2 is regulated independently from IDI1, by a mechanism that may involve PPAR-alpha.
    Alternative Names: Isopentenyl-Diphosphate Delta-Isomerase 2, Isopentenyl Pyrophosphate Isomerase 2, IPP Isomerase 2, IPPI2, IDI2
    Molecular Weight
    28.9 kDa
    UniProt
    Q9BXS1
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