LRRN3 Protein (His tag)

Catalog No. ABIN7317526

Product Details

Target: LRRN3 (Leucine Rich Repeat Neuronal 3 (LRRN3))

Protein Type: Recombinant

Origin: Human

Source: Baculovirus infected Insect Cells

Purification tag / Conjugate: This LRRN3 protein is labelled with His tag.

Purpose: Recombinant Human LRRN3 Protein (His Tag)

Sequence: Met 1-Thr 628

Characteristics: A DNA sequence encoding the human LRRN3 (AAH35133.1) extracellular domain (Met 1-Thr 628) was fused with a polyhistidine tag at the C-terminus.

Purity: > 90 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 7.0, 10 % glycerol

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: LRRN3 (Leucine Rich Repeat Neuronal 3 (LRRN3))

Alternative Name: LRRN3 (LRRN3 Products)

Synonyms: nlrr3 Protein, nlrr-3 Protein, MGC146637 Protein, FIGLER5 Protein, NLRR-3 Protein, NLRR3 Protein, Nlrr3 Protein, leucine rich repeat neuronal 3 Protein, leucine rich repeat protein 3, neuronal Protein, LRRN3 Protein, lrrn3 Protein, Lrrn3 Protein

Background:

Background: Leucine-rich repeat neuronal protein 3, also known as neuronal leucine-rich repeat protein 3 (NLRR-3), is a member of leucine-rich (LRR) family whose members have significant functions in neural development. Leucine-rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. All proteins containing these repeats are thought to be involved in protein-protein interactions. The crystal structure of ribonuclease inhibitor protein has revealed that leucine-rich repeats correspond to β-α structural units. These units are arranged so that they form a parallel β-sheet with one surface exposed to solvent, so that the protein acquires an unusual, non-globular shape. These two features may be responsible for the protein-binding functions of proteins containing leucine-rich repeats. LRRN3 plays an important role in cerebellum postnatal development. In a unilateral cortical injury cerebral cortex, NLRR-3 mRNA increased in layers 2-3 which suggests that NLRR-3 may be an important component of the pathophysiological response to brain injury. 

Synonym: FIGLER5;NLRR-3;NLRR3

Molecular Weight: 70 kDa