LYPD3 Protein (His tag)
-
- Target See all LYPD3 products
- LYPD3 (LY6/PLAUR Domain Containing 3 (LYPD3))
- Protein Type
- Recombinant
- Biological Activity
- Active
-
Origin
- Human
-
Source
- Human Cells
- Purification tag / Conjugate
- This LYPD3 protein is labelled with His tag.
- Purpose
- Recombinant Human LYPD3 Protein (His Tag)(Active)
- Sequence
- Leu31-His286
- Characteristics
- Recombinant Human Ly6/PLAUR Domain-Containing Protein 3 is produced by our Mammalian expression system and the target gene encoding Leu31-His286 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Immobilized Human LGALS3(Cat: PKSH032474) at 0.5μg/ml(100 μl/well) can bind Human LYPD3-His.
-
LY6/PLAUR Domain Containing 3 (LYPD3) (AA 31-286) protein (His tag)
LYPD3 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
LY6/PLAUR Domain Containing 3 (LYPD3) (AA 33-287) protein (His tag)LYPD3 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
LY6/PLAUR Domain Containing 3 (LYPD3) (AA 1-346) protein (GST tag)LYPD3 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
LY6/PLAUR Domain Containing 3 (LYPD3) (Active) protein (His tag)LYPD3 Origin: Mouse Host: HEK-293 Cells Recombinant > 92 % as determined by SDS-PAGE Active
LY6/PLAUR Domain Containing 3 (LYPD3) (AA 31-326) protein (His tag)Crystallography grade LYPD3 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
LY6/PLAUR Domain Containing 3 (LYPD3) (AA 33-343) protein (His tag)Crystallography grade LYPD3 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
- Target
- LYPD3 (LY6/PLAUR Domain Containing 3 (LYPD3))
- Alternative Name
- LYPD3 (LYPD3 Products)
- Synonyms
- LYPD3 Protein, MGC139913 Protein, C4.4A Protein, 2310061G07Rik Protein, C4.4a Protein, LY6/PLAUR domain containing 3 Protein, Ly6/Plaur domain containing 3 Protein, LYPD3 Protein, Lypd3 Protein
- Background
-
Background: Ly6/PLAUR domain containing3 (LYPD-3) is a GPI-linked protein. The structure of LYPD-3 is similar to the urokinasetype plasminogen activator receptor (uPAR). LYPD-3 is a 6 -100 kDa molecule with variable cell type-specific N-O-linked glycosylation, mature human LYPD-3 contains two uPAR/Ly6 domains and a Ser/Thr/Pro-rich (STP) region includes a protease sensitive site . The interaction of LYPD-3 with Laminin 1 and 5 on neighboring cells promotes the adhesion, spreading, and migration of tumor cells. LYPD-3 additionally interacts with Galectin-3 and the anterior gradient proteins AG-2 and AG-3. LYPD-3 overexpression in non-small cell lung cancer is predictive of increased mortality.
Synonym: Ly6/PLAUR Domain-Containing Protein 3, GPI-Anchored Metastasis-Associated Protein C4.4A Homolog, Matrigel-Induced Gene C4 Protein, MIG-C4, LYPD3, C4.4A
- Molecular Weight
- 27.9 kDa
- NCBI Accession
- NP_055215
-
