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MMP3 Protein (His tag)

MMP3 Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7319525
  • Target See all MMP3 Proteins
    MMP3 (Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3))
    Protein Type
    Recombinant
    Origin
    • 21
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Source
    • 26
    • 5
    • 4
    • 2
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This MMP3 protein is labelled with His tag.
    Purpose
    Recombinant Human MMP-3 Protein (His Tag)
    Sequence
    Tyr18-Cys477(Lys45Glu)
    Characteristics
    Recombinant Human MMP-3 is produced by our Mammalian expression system and the target gene encoding Tyr18-Cys477(Lys45Glu) is expressed with a 6His tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product MMP3 Protein
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, 0.05 % Brij35, 10 % Glycerol, pH 7.5.
    Storage
    -20 °C
    Storage Comment
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    MMP3 (Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3))
    Alternative Name
    MMP-3 (MMP3 Products)
    Synonyms
    CHDS6 Protein, MMP-3 Protein, SL-1 Protein, STMY Protein, STMY1 Protein, STR1 Protein, SLN-1 Protein, SLN1 Protein, STR-1 Protein, Stmy1 Protein, Str1 Protein, MMP10 Protein, chds6 Protein, mmp-3 Protein, mmp13 Protein, mmp3 Protein, sl-1 Protein, stmy Protein, stmy1 Protein, str1 Protein, matrix metallopeptidase 3 Protein, matrix metallopeptidase 3 (stromelysin 1, progelatinase) Protein, matrix metallopeptidase 3 L homeolog Protein, MMP3 Protein, Mmp3 Protein, mmp3.L Protein
    Background

    Background: MMP3 is a member of the matrix metalloproteinase (MMP) family whose members are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, tissue remodeling, and disease processes including arthritis and metastasis. The MMP-3 enzyme degrades collagen types II, III, IV, IX, and X, proteoglycans, fibronectin, laminin, and elastin. In addition, MMP-3 can also activate other MMPs such as MMP-1, MMP-7, and MMP-9, rendering MMP-3 crucial in connective tissue remodeling.[3] The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation.

    Synonym: Stromelysin-1, SL-1, Matrix metalloproteinase-3,Transin-1, MMP3, STMY1,CHDS6,MMP-3,SL-1,STMY,STR1

    Molecular Weight
    53.26 kDa
    UniProt
    P08254
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