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MINPP1 Protein (His tag)

MINPP1 Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7318790
  • Target See all MINPP1 Proteins
    MINPP1 (Multiple Inositol-Polyphosphate Phosphatase 1 (MINPP1))
    Protein Type
    Recombinant
    Origin
    • 9
    • 3
    • 2
    • 1
    Human
    Source
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This MINPP1 protein is labelled with His tag.
    Purpose
    Recombinant Human MINPP1 Protein (His Tag)
    Sequence
    Ser31-Leu487
    Characteristics
    Recombinant Human Multiple Inositol Polyphosphate Phosphatase 1 is produced by our Mammalian expression system and the target gene encoding Ser31-Leu487 is expressed with a 6His tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product MINPP1 Protein
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, 10 % Glycerol, pH 7.5.
    Storage
    -20 °C
    Storage Comment
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    MINPP1 (Multiple Inositol-Polyphosphate Phosphatase 1 (MINPP1))
    Alternative Name
    MINPP1 (MINPP1 Products)
    Synonyms
    HIPER1 Protein, MINPP2 Protein, MIPP Protein, AA408516 Protein, minpp1 Protein, zgc:56080 Protein, zgc:76991 Protein, zgc:153026 Protein, multiple inositol-polyphosphate phosphatase 1 Protein, multiple inositol polyphosphate histidine phosphatase 1 Protein, multiple inositol-polyphosphate phosphatase 1b Protein, multiple inositol-polyphosphate phosphatase 1a Protein, MINPP1 Protein, Minpp1 Protein, minpp1b Protein, minpp1a Protein
    Background

    Background: Multiple Inositol Polyphosphate Phosphatase 1/MINPP1 is an enzyme that removes 3-phosphate from inositol phosphate substrates. MINPP1 also converts 2,3 bisphosphoglycerate (2,3-BPG) to 2-phosphoglycerate. MINPP1 is synthesized as a 487 amino acid precursor that contains an 30 amino acid signal peptide and a 457 amino aicd mature chain. MINPP1 is widely expressed with the highest levels found in kidney, liver and placenta. It acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). MINPP1 may play a role in bone development (endochondral ossification).

    Synonym: Multiple Inositol Polyphosphate Phosphatase 1, 2,3-Bisphosphoglycerate 3-Phosphatase, 2,3-BPG Phosphatase, Inositol (1,3,4,5)-Tetrakisphosphate 3-Phosphatase, Ins(1,3,4,5)P(4) 3-Phosphatase, MINPP1, MIPP

    Molecular Weight
    53.1 kDa
    UniProt
    Q9UNW1
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