NAALADL1 Protein (His tag)
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- Target See all NAALADL1 Proteins
- NAALADL1 (N-Acetylated alpha-Linked Acidic Dipeptidase-Like 1 (NAALADL1))
- Protein Type
- Recombinant
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This NAALADL1 protein is labelled with His tag.
- Purpose
- Recombinant Mouse NAALADL1 Protein (His Tag)
- Sequence
- Pro 29-Leu 745
- Characteristics
- A DNA sequence encoding the secreted form of mouse NAALADL1 (Q7M758) (Pro 29-Leu 745) was fused with a polyhistidine tag at the N-terminus.
- Purity
- > 97 % as determined by SDS-PAGE
- Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
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N-Acetylated alpha-Linked Acidic Dipeptidase-Like 1 (NAALADL1) (AA 1-740) protein (Strep Tag)
Crystallography grade NAALADL1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
N-Acetylated alpha-Linked Acidic Dipeptidase-Like 1 (NAALADL1) (AA 1-745) protein (Strep Tag)Crystallography grade NAALADL1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
N-Acetylated alpha-Linked Acidic Dipeptidase-Like 1 (NAALADL1) (AA 29-740) protein (His tag)Crystallography grade NAALADL1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB, Crys
N-Acetylated alpha-Linked Acidic Dipeptidase-Like 1 (NAALADL1) (AA 29-745) protein (His tag)Crystallography grade NAALADL1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB, Crys
N-Acetylated alpha-Linked Acidic Dipeptidase-Like 1 (NAALADL1) protein (Myc-DYKDDDDK Tag)NAALADL1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- NAALADL1 (N-Acetylated alpha-Linked Acidic Dipeptidase-Like 1 (NAALADL1))
- Alternative Name
- NAALADL1 (NAALADL1 Products)
- Synonyms
- I100 Protein, NAALADASEL Protein, Gm964 Protein, Naaladasel Protein, N-acetylated alpha-linked acidic dipeptidase like 1 Protein, N-acetylated alpha-linked acidic dipeptidase-like 1 Protein, NAALADL1 Protein, Naaladl1 Protein
- Background
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Background: N-acetylated-alpha-linked acidic dipeptidase-like protein, also known as NAALADL1, NAALADase L, and Ileal dipeptidylpeptidase, is a Single-pass type I I membrane protein and a member of the peptidase M28 family and M28B subfamily. NAALADase L is mainly expressed in the distal small intestine. It is also expressed in the spleen and testis and Weakly expressed in the brain, locating mainly to the brain stem, amygdala, thalamus and ventral striatum. NAALADase L is a chloride-activated, membrane bound, metallopeptidase that cleaves the endogenous neuropeptide N-acetyl-aspartyl-glutamate (NAAG). NAAG acts as a partial NMDA agonist as well as a full agonist at the presynaptic metabotropic glutamate receptor 3 (mGluR3), where it acts to reduce glutamate release. NAALADase L also exhibits a dipeptidyl-peptidase IV type activity. NAALADase inhibition may be a novel therapeutic approach to reduce or inhibit heightened aggressiveness, and possibly to treat aggressive behavior associated with psychiatric disorders.
Synonym: Gm964,Naaladasel
- Molecular Weight
- 80 kDa
- UniProt
- Q7M758
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